Sökning: "molecularly imprinted polymers"

Visar resultat 16 - 20 av 37 avhandlingar innehållade orden molecularly imprinted polymers.

  1. 16. QCM-based sensing using biological and biomimetic interfaces

    Författare :Louise Elmlund; Ian Nicholls; Teodor Aastrup; Jesper Wiklander; Kristina Nilsson-Ekdahl; Håkan Andersson; Susanne Wikman; Alessandra Maria Bossi; Linnéuniversitetet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Quartz crystal microbalance; molecularly imprinted polymers; phage display; interactions; artificial receptors; recognition; selectivity; Kemi; Chemistry;

    Sammanfattning : The objective of this thesis was to explore novel approaches for studying molecular recognition at biological and biomimetic surfaces using the quartz crystal microbalance (QCM) biosensor technique. The first two papers focused on the synthesis and study of biotin selective polymer films prepared using the molecularly imprinted polymer (MIP) technique. LÄS MER

  3. 17. Connecting sialic acid expression to cancer cell characteristics : Novel tools for detection, imaging, and analysis

    Författare :Louise Sternbæk; Anette Gjörloff Wingren; Kersti Alm; Birgit Janicke; Håkan Eriksson; Magnus Abrahamson; Malmö universitet; []
    Nyckelord :Molecularly imprinted polymers; digital holographic cytometry; cancer; cytotoxicity; inflammation; sialic acid; Health and society; Hälsa och samhälle;

    Sammanfattning : Sialic acid (SA) plays a crucial role in many biological processes. Cell surface SA expression is usually analyzed with antibodies or lectins; however, they are costly and with poor stability. LÄS MER

  4. 18. Utility of novel drug targets for treatment of metastatic cancer

    Författare :Tianyan Wang; Jenny Persson; Thomas Grundström; Maréne Landström; Margareta Wilhelm; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Metastatic cancer; castration-resistant prostate cancer; pancreatic ductal adenocarcinoma; target therapy; PIP5K1α; KRAS; molecularly imprinted polymers; Oncology; onkologi; molekylärbiologi; Molecular Biology; Medical Cell Biology; medicinsk cellbiologi;

    Sammanfattning : Metastasis is the leading cause of cancer death because of a lack of early diagnosis tools and efficient treatment drugs. The lipid kinase phosphatidylinositol 4-phosphate 5 kinase (PIP5K1α) has been shown to play a vital role in the PI3K/AKT and KRAS signaling pathways. LÄS MER

  5. 19. Towards novel applications for biomolecular interactions at surfaces

    Författare :Pernilla Söderberg; Karl Hult; Linnéuniversitetet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; molecular recognition; interactions; phage display; biomolecular interactions; phage; adenine; influenza virus replication; oseltamivir; imprinted polymers.;

    Sammanfattning : The focus of this thesis has been to examine two new concepts involving the interaction of biological agents with synthetic material surfaces.The feasibility of deploying phage display techniques for the screening of materials in non-biological media was examined in two studies. LÄS MER

  7. 20. Glycosylation in cancer and infection : the role of sialic acid

    Författare :Yuecheng Zhang; Anette Wingren; Maria Stollenwerk; Lars Ohlsson; Martin Dufva; Malmö universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Cancer; sialic acids; receptor; molecularly imprinted polymers; SARS-CoV-2; fluorescence; Health and society; Hälsa och samhälle;

    Sammanfattning : Sialic acids (SA), a group of nine-carbon backbone monosaccharides are abundantly expressed in vertebrates. They are usually linked to the terminal of glycan chains and play crucial roles in many biological processes, including cell adhesion, cell-cell interactions, immune modulation, cancer cell migration and invasion, as well as viral infections. LÄS MER