Sökning: "biomolecular interactions"

Visar resultat 1 - 5 av 77 avhandlingar innehållade orden biomolecular interactions.

  1. 1. Modelling biomolecular interactions

    Författare :Johan Bredenberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Computational chemistry; molecular dynamics; nuclear receptors; force field parameterization; zinc fingers; DNA; proteins.;

    Sammanfattning : Computational approaches for understanding and aiding in molecular biology has increased in significance over the last decades, where a wealth of biochemical experiments have provided a solid ground for developing computer models that can be used to predict unresolved issues within biology. Molecular dynamics (MD) is one of these methods, based on classical laws, and suitable for handling large macromolecules in their natural environment, water. LÄS MER

  3. 2. Towards novel applications for biomolecular interactions at surfaces

    Författare :Pernilla Söderberg; Karl Hult; Linnéuniversitetet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; molecular recognition; interactions; phage display; biomolecular interactions; phage; adenine; influenza virus replication; oseltamivir; imprinted polymers.;

    Sammanfattning : The focus of this thesis has been to examine two new concepts involving the interaction of biological agents with synthetic material surfaces.The feasibility of deploying phage display techniques for the screening of materials in non-biological media was examined in two studies. LÄS MER

  4. 3. Biomolecular interactions at model interfaces : a self-assembled monolayer approach

    Författare :Sofia Svedhem; Linköpings universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : The overall aim of this thesis has been to explore the use of self-assembled monolayers (SAMs) in model studies of biomolecular binding at interfaces. Molecular details of interfaces are difficult to address experimentally, and in spite of the fact that interactions in the living system commonly occur at interfaces, e.g. LÄS MER

  5. 4. Biomolecular Interactions with Porous Silicon

    Författare :Linda Karlsson; Martin Malmsten; Linköpings universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : One common problem when putting something inside the body is a fast response from the body defending it from the intruder. Here the researchers are struggling with finding biocompatible materials, which act in a predicted and non-harmful way. LÄS MER

  7. 5. QCM-D – with focus on biosensing in biomolecular and cellular systems

    Författare :Erik Nilebäck; Chalmers tekniska högskola; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; QCM-D; biomolecular interactions; cell-surface interaction; glycosaminoglycans; viscoelasticity; cell morphology; Quartz crystal microbalance with dissipation monitoring; surface chemistry; protein conformation;

    Sammanfattning : The high degree of complexity in biological systems is being investigated in greater and greater detail by increasingly sophisticated sensing approaches. The quartz crystal microbalance with dissipation monitoring (QCM-D) technique stands out in this context, by probing the viscoelastic properties at interfaces. LÄS MER