Sökning: "mediated actions"

Visar resultat 11 - 15 av 160 avhandlingar innehållade orden mediated actions.

  1. 11. Vasodilator actions of EDHF and anandamide

    Författare :David Andersson; Avdelningen för klinisk kemi och farmakologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; vanilloid receptors; afferent neurons; anandamide; cannabinoids; potassium channels; hyperpolarization; vasodilation; Vascular endothelium; arteries; airways; Pharmacological sciences; pharmacognosy; pharmacy; toxicology; Farmakologi; farmakognosi; farmaci; toxikologi;

    Sammanfattning : Vasodilator responses to endothelium-derived hyperpolarizing factor (EDHF) and anandamide in isolated arteries were investigated. A combination of the potassium channel blockers charybdotoxin and apamin inhibits EDHF-mediated relaxations. LÄS MER

  3. 12. Immunological, vascular and metabolic actions of androgens

    Författare :Marta Lantero Rodriguez; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; androgens; androgen receptor; immune system; atherosclerosis; abdominal aortic aneurysm; brown fat; mice;

    Sammanfattning : Men have higher prevalence of cardiovascular disease (CVD) but lower risk of autoimmune disorders than women. The actions of sex steroids may be involved in the sexual dimorphism of these diseases. Although testosterone, the main androgen, seems to protect against autoimmunity, its role in CVD is contradictory and disease-dependent. LÄS MER

  4. 13. Estrogen actions in the growth plate cartilage

    Författare :Maryam Iravani; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Estrogens may influence bone growth locally or systemically via the estrogen receptors alpha (ERα), beta (ERβ) and G protein-coupled estrogen receptor 1 (GPER-1). In Paper I, our study showed that the treatment of ovariectomized C57BL/6 mice with a selective ERα agonist 1,3,5-tris(4-hydroxyphenyl)-4-propyl-1H-pyrazole (PPT) reduced growth plate height and hypertrophic zone height suggesting that the effect was induced via ERα. LÄS MER

  5. 14. Mellan "jag" och andra. Nätbaserade studentdialoger med argumentering och responsgivning för lärande

    Författare :Lisbeth Amhag; Malmö högskola; []
    Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Cooperative collaborative learning; Computer-mediated communication; Distributed learning environments; Interactive learning environments; Learning communities; distributed learning environments; web-based dialogues; learning communities; computer-mediated communication; interactive learning environments; cooperative collaborative learning;

    Sammanfattning : Avhandlingen handlar om kvaliteten i studenters nätbaserade argumentering och responsgivning. Handlar det om vardagssamtal eller vetenskapliga diskussioner? Syftet är att undersöka om och i så fall hur studenters skriftliga, asynkrona dialoger bidrar till utveckling av kollektivt och individuellt lärande i en nätbaserad akademisk kontext. LÄS MER

  7. 15. DNA-Mediated Detection and Profiling of Protein Complexes

    Författare :Maria Hammond; Ulf Landegren; Masood Kamali-Moghaddam; Christof Niemeyer; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Proximity ligation assay; Protein complexes; Protein interactions; Biomarkers; Prions; Antibodies; Medicinsk vetenskap; Medical Science;

    Sammanfattning : Proteins are the effector molecules of life. They are encoded in DNA that is inherited from generation to generation, but most cellular functions are executed by proteins. Proteins rarely act on their own – most actions are carried out through an interplay of tens of proteins and other biomolecules. LÄS MER