Sökning: "mediated actions"

Visar resultat 21 - 25 av 160 avhandlingar innehållade orden mediated actions.

  1. 21. Actions of androgens and estrogens in experimental models of cardiovascular disease

    Författare :Johan Bourghardt Fagman; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; AR; atherosclerosis; AAA; androgens; testosterone; 2-methoxyestradiol;

    Sammanfattning : Men are at higher risk of developing both atherosclerotic cardiovascular disease and abdominal aortic aneurysm (AAA). Actions of sex steroids are hypothesized to underlie these gender differences. Testosterone, the major androgen, reduces atherosclerosis in male animal models but is suggested to promote AAA formation. LÄS MER

  3. 22. Effects and mechanisms of actions of cyclosporin, FK506 and 15-deoxyspergualin

    Författare :Anette Johansson Borg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :cyclosporin; FK506; 15-deoxyspergualin; immunosuppressive effects; transplantation;

    Sammanfattning : Immunosuppressive drugs can be used to deal with unwanted or inappropriate immune reactions, such as the rejection of a transplanted organ. However, treatment with these drugs are often associated with serious adverse effects, and therefore less toxic immunosuppressants are desired. LÄS MER

  4. 23. Signal transduction in the brain : modulation of receptor-mediated inositol phospholipid breakdown by potassium and fluoride ions

    Författare :Gunnar Tiger; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Inositol phospholipid breakdown; muscarinic receptors; potassium; fluoride; rat brain; pig brain;

    Sammanfattning : Neurotransmitter receptor types mediating the generation of intracellular signals are of two types; ligand-gated ion channels and G protein coupled receptors. The effector enzyme phosphoinositide-specific phospholipase C (PLC) is modulated by stimulation of G protein coupled receptors, leading to an increased breakdown of inositol phospholipids ("Ptdlns breakdown"). LÄS MER

  5. 24. Digital technologies in preschool education : The interplay between interactive whiteboards and teachers' teaching practices

    Författare :Maryam Bourbour; Ann Quennerstedt; Gunilla Lindqvist; Sören Högberg; Sylvana Sofkova Hashemi; Högskolan Dalarna; []
    Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Preschool Teachers; Digital Technologies; IWB; Teaching; Children; Preschools; Scaffolding; Mediational Means and Mediated Actions; Utbildning och lärande; Education and Learning;

    Sammanfattning : This thesis is aimed at exploring the ways in which a digital technology, the interactive whiteboard (IWB), interplays with preschool teachers’ teaching practices. In the literature and ongoing debates there are different claims about if and how digital technologies can contribute to children’s development and solving preschool educational challenges. LÄS MER

  7. 25. The role of nitric oxide in cytoskeleton-mediated organelle transport and cell adhesion

    Författare :Harriet Nilsson; David Sugden; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Nitric oxide (NO) is a signaling molecule that is produced by many different kinds of cells, and it is known to mediate actions such as blood vessel dilation, communication between nerve cells, and killing of bacteria in infections. The cytoskeleton is involved in many important cellular functions, among them intracellular transport of organelles, migration, and cell division. LÄS MER