Sökning: "mast cells"

Visar resultat 1 - 5 av 178 avhandlingar innehållade orden mast cells.

  1. 1. Mast Cells as Sentinels : Role of serglycin and mast cell proteases in infection and inflammation

    Författare :Ananya Roy; Magnus Åbrink; Olaf Utermöhlen; Uppsala universitet; []
    Nyckelord :mast cells; serglycin; chymase; infection; parasite; Immunologi; Immunology;

    Sammanfattning : Mast cells (MCs), normally classified into connective tissue MCs and mucosal MCs, are highly granulated cells found in the interface between the interior and the exterior environment of our body, e.g. skin, airways and gastro-intestinal tract. LÄS MER

  3. 2. Induction of Mast Cell Apoptosis via Granule Permeabilization : A Novel Approach to Target Mast Cells

    Författare :Aida Paivandy; Gunnar Pejler; Magda Babina; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Mast cells; Granules; Apoptosis; Reactive oxygen species; ROS; Lysosomotropic agents; Mefloquine; Immunologi; Immunology; Biokemi; Biochemistry;

    Sammanfattning : Mast cells are densely granulated tissue-resident immune cells that play an important role in orchestrating inflammatory responses. Dysregulated increases in the numbers and activation status of mast cells can have deleterious consequences for the body in various inflammatory diseases. LÄS MER

  4. 3. Mast cells in Hodgkin lymphoma : or 'What's a nice cell like you doing in a tumour like this?'

    Författare :Marie Fischer; Gunnar Nilsson; Gunilla Enblad; Tor Olofsson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pathology; Hodgkin lymphoma; mast cells; CD30; CD30L; IL-9; CCL5; atopic dermatitis; psoriasis; IL-8; Patologi; Pathology; Patologi;

    Sammanfattning : Mast cell (MC) accumulation around tumours is an old observation gaining new relevance due to the multifaceted nature of MCs and their many roles in immunity, beyond allergy. Knowledge about tumour specific recruitment of, and interactions with, MCs is needed to unravel the function of their presence. LÄS MER

  5. 4. Bystander Cells and Prognosis in Hodgkin Lymphoma

    Författare :Daniel Molin; Stephen J. Proctor; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oncology; Hodgkin Lymphoma; Bystander cells; Eosinophilic granulocytes; Eosinophil cationic protein ECP ; Mast cells; Prognosis; Early and Intermediate stage; Onkologi; Hodgkin lymfom; eosinofila granulocyter; ECP; mast celler; prognos; tidiga och intermediära stadier; Oncology; Onkologi; Oncology; onkologi;

    Sammanfattning : Hodgkin lymphoma (HL) is characterised histologically by a minority of malignant Hodgkin and Reed-Sternberg (HRS) cells surrounded by benign cells, and clinically by a relatively good prognosis. The treatment, however, leads to a risk of serious side effects. LÄS MER

  7. 5. Mast cells and their progenitors in respiratory diseases : Understanding their connection to lung function and airway inflammation

    Författare :P. Abigail Alvarado-Vazquez; Jenny Hallgren; Arne Egesten; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mast cells; mast cell progenitors; pulmonary function test; allergic airway inflammation; experimental asthma model; Immunologi; Immunology;

    Sammanfattning : Mast cells are rare immune cells involved in allergic diseases, including asthma. These cells are derived from mast cell progenitors (MCps) that migrate to the peripheral tissues via the blood in response to allergic or non-allergic stimuli. LÄS MER