Sökning: "experimental asthma model"

Visar resultat 1 - 5 av 20 avhandlingar innehållade orden experimental asthma model.

1. 1. Immunoregulation in an experimental model of allergic asthma

   Författare :Magnus Korsgren; Avdelningen för klinisk kemi och farmakologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; allergic asthma; macrophage migration inhibitory factor; eosinophils; gd T cells; NK1.1 T cells; natural killer cells; immunoglobulins; B cells; innate immunity; allergic airway inflammation; immediate hypersensitivity; Physiology; Fysiologi; Immunology; serology; transplantation; Immunologi; serologi;

   Sammanfattning : In allergic asthma the immune response to antigen is inappropriate, leading to an inflammatory process in the respiratory mucosa. To further elucidate immunological mechanisms involved in the development of such inflammation, control mice and mice deficient in selected cell types or proteins, were used in experimental models of allergic asthma and anaphylaxis. LÄS MER

3. 2. Eosinophil Inflammation in Allergic Disease : Clinical and experimental studies in allergic asthma and allergic rhinitis

   Författare :Mary Kämpe; Marie Carlson; Christer Janson; Gunnemar Stålenheim; Magnus Sköld; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Allergic asthma; allergic rhinitis; eosinophils; pollen season; bronchial challenge; nasal challenge eosinophil degranulation; PI3K signalling; Allergology; Allergologi; Lung Medicine; Lungmedicin; Lung Medicine; Lungmedicin;

   Sammanfattning : Allergic diseases are chronic inflammatory conditions, characterised by eosinophil inflammation systemically and in target organs, where cytotoxic granule proteins are responsible for tissue injury. Allergic rhinitis is known to be a risk factor for the development of asthma, yet not all with rhinitis develop asthma. LÄS MER

4. 3. Mast cells and their progenitors in respiratory diseases : Understanding their connection to lung function and airway inflammation

   Författare :P. Abigail Alvarado-Vazquez; Jenny Hallgren; Arne Egesten; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mast cells; mast cell progenitors; pulmonary function test; allergic airway inflammation; experimental asthma model; Immunologi; Immunology;

   Sammanfattning : Mast cells are rare immune cells involved in allergic diseases, including asthma. These cells are derived from mast cell progenitors (MCps) that migrate to the peripheral tissues via the blood in response to allergic or non-allergic stimuli. LÄS MER

5. 4. Neurotrophins and nitric oxide in relation to airway responses in experimental asthma in vivo

   Författare :Lydia Bennedich Kahn; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Asthma is an inflammatory disease of allergic or non-allergic genesis characterized by intermittent reversible airway obstruction and variable degrees of persistent airway hyperresponsiveness (AHR). Increase in AHR likely arises from augmented airway inflammation, such as associated with a late airway response. LÄS MER

7. 5. Aiway Mucins: experimental models for studies of secretions

   Författare :Naila Svitacheva; Institutionen för experimentell medicinsk vetenskap; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cystic fibrosis; bovine trachea; radiolabelling; cell line; primary cell culture; organ culture; mucus; mucin; Endocrinology; secreting systems; diabetology; Endokrinologi; sekretion; diabetologi;

   Sammanfattning : Mucins are essential components of the mucosal barrier. The complexity of the airway mucosal barrier is reflected in the lack of specific treatments to block mucin hypersecretion associated with several respiratory diseases such as chronic bronchitis, asthma and cystic fibrosis. LÄS MER