Sökning: "Eosinophil cationic protein ECP"

Visar resultat 1 - 5 av 25 avhandlingar innehållade orden Eosinophil cationic protein ECP.

1. 1. Eosinophil Cationic Protein : Expression Levels and Polymorphisms

   Författare :Jonas Byström; Helene Rosenberg; Uppsala universitet; []
   Nyckelord :Medical sciences; Eosinophils; Neutrophils; Monocytes; Macrophages; mRNA; eosinophil cationic protein; DNA; polymorphism; Hodgkin Lymphoma; asthma; allergy; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Clinical Chemistry; klinisk kemi;

   Sammanfattning : The eosinophil cationic protein (ECP) is usually associated with the eosinophil granulocyte. In this thesis the presence and production of this protein has been studied in two other cells. The circulating monocyte was found to contain ECP mRNA and small amounts of ECP, one thousand times less than that found in the eosinophil. LÄS MER

3. 2. Studies of Eosinophil Cationic Protein (ECP) in vivo and in vitro : Impact of Genetic and Posttranslational Modifications

   Författare :Jenny Eriksson; Per Venge; Agneta Trulson; Ester Boix; Uppsala universitet; []
   Nyckelord :Biomedicine; Eosinophil granulocyte; granular protein; ECP; gene polymorphism; cytotoxicity; SELDI-TOF MS; glycosylation; molecular and functional heterogeneity; fibrosis; Biomedicin;

   Sammanfattning : Eosinophil granulocytes are tissue dwelling leukocytes that are implicated in host defence, particularly against helminthic parasites; they also participate in most inflammatory disorders. Although eosinophils have important roles in host defence mechanisms, their actions can also be harmful to the host as in the allergic inflammation where lung epithelium is destructed due to the release of toxic granule proteins. LÄS MER

4. 3. Inflammation in asthma: relation to symptomatology, exacerbations and lung function

   Författare :Ida Mogensen; Andrei Malinovschi; Christer Jansson; Mona Bafadhel; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Asthma; eosinophil; eosinophil cationic protein; eosinophil derived neurotoxin; periostin; neutrophil; fixed airflow obstruction; lung function; asthma attack; asthma symptom;

   Sammanfattning : Asthma is an inflammatory disease in the airways. It is characterized by respiratory symptoms such as wheezing, variable airflow obstruction and impaired lung function development. A better understanding of the underlying inflammation is crucial in order to treat and prevent asthma symptoms and lung function deterioration. LÄS MER

5. 4. Clinical and Experimental Studies on Inflammatory Bowel Disease with special emphasis on Collagenous Colitis

   Författare :Michael Wagner; Marie Carlson; Maria Lampinen; Per Sangfelt; Erik Hertervig; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Collagenous colitis; inflammatory bowel disease; ulcerative colitis; Crohn´s disease; faecal markers; eosinophil; T-cells; ECP; EPX; MPO; calprotectin; flowcytometry; chromogranin A; chromogranin B; secretoneurin; budesonide; Gastroenterology; Gastroenterologi; Medicin; Medicine;

   Sammanfattning : This thesis describes studies in patients with inflammatory bowel disease (IBD) and collagenous colitis (CC). We investigated mucosal eosinophil and neutrophil granulocytes and T-cells involved in the inflammatory processes and aimed at determining whether these processes are reflected in the faecal (F) contents of specific proteins secreted by cells in the intestinal mucosa. LÄS MER

7. 5. Bystander Cells and Prognosis in Hodgkin Lymphoma

   Författare :Daniel Molin; Stephen J. Proctor; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oncology; Hodgkin Lymphoma; Bystander cells; Eosinophilic granulocytes; Eosinophil cationic protein ECP ; Mast cells; Prognosis; Early and Intermediate stage; Onkologi; Hodgkin lymfom; eosinofila granulocyter; ECP; mast celler; prognos; tidiga och intermediära stadier; Oncology; Onkologi; Oncology; onkologi;

   Sammanfattning : Hodgkin lymphoma (HL) is characterised histologically by a minority of malignant Hodgkin and Reed-Sternberg (HRS) cells surrounded by benign cells, and clinically by a relatively good prognosis. The treatment, however, leads to a risk of serious side effects. LÄS MER