Sökning: "Mefloquine"
Visar resultat 1 - 5 av 10 avhandlingar innehållade ordet Mefloquine.
1. Induction of Mast Cell Apoptosis via Granule Permeabilization : A Novel Approach to Target Mast Cells
Sammanfattning : Mast cells are densely granulated tissue-resident immune cells that play an important role in orchestrating inflammatory responses. Dysregulated increases in the numbers and activation status of mast cells can have deleterious consequences for the body in various inflammatory diseases. LÄS MER
2. Development of Analytical Methods for the Determination of Antimalarials in Biological Fluids
Sammanfattning : The aim of this thesis was to develop analytical methods for measuring antimalarial drugs in biological fluids. Solid phase extraction (SPE) was used for the enrichment and purification of the drugs. LÄS MER
3. Determination of Mefloquine Enantiomers and their Main Metabolite in Biological Fluids
Sammanfattning : .... LÄS MER
4. Enantioseparation of drugs and related compounds using chiral mobile phase additives
Sammanfattning : Neutral and anionic chiral mobile phase additives have been employed to separate enantiomers of drugs and related compounds using aqueous buffer solution and hydro-organic solvent mixtures as mobile phases.Ester derivatives of tartaric acid, e. g. LÄS MER
5. Experimental pharmacodynamic and kinetic studies related to new combination therapies against P. falciparum malaria
Sammanfattning : Artemisinin (ART) class of compounds are of special interest due to their rapid onset of action and high activity against multidrug resistant malaria. The major drawback in monotherapy with ART and its derivatives is the high rate of recrudescent infection. LÄS MER