Sökning: "mast cell progenitors"

Visar resultat 1 - 5 av 11 avhandlingar innehållade orden mast cell progenitors.

  1. 1. The Role of Chemokines in Mast Cell Migration

    Författare :Mikael Juremalm; Timothy J. Williams; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pathology; Mast cells; chemotaxis; calcium flux; chemokines and chemokine receptors; Patologi; Pathology; Patologi; Pathology; patologi;

    Sammanfattning : Mast cells are very potent multifunctional effector cells of the immune system normally distributed throughout connective tissues. An accumulation of mast cells has been described in several pathological conditions such as allergic- and autoimmune inflammations and in certain tumours. LÄS MER

  3. 2. Mechanisms triggering the recruitment of mast cell progenitors to the lung and regulation of mast cell degranulation

    Författare :Behdad Zarnegar; Jenny Hallgren; Madeleine Rådinger; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Mast cells; Mast cell progenitors; Recruitment; Lung; Virus; Influenza; Innate immunity; Poly I:C; IL-33; VAAT; SLC10A4; Degranulation;

    Sammanfattning : Mast cells stem from the bone marrow and migrate via the blood as mast cell progenitors. Upon arrival in peripheral tissues, they develop into mast cells. These rare immune cells have numerous granules that contain large amounts of pro-inflammatory mediators. LÄS MER

  4. 3. Mast Cell Progenitor Trafficking in Allergic Airway Inflammation

    Författare :Joakim Dahlin; Jenny Hallgren; Hans-Reimer Rodewald; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Mast cells; mast cell progenitors; allergy; asthma; allergic airway inflammation; IgE; lung; CD11c;

    Sammanfattning : Mast cell progenitors originate from the bone marrow and migrate to the lungs via the blood. During maturation, these cells acquire granules that contain a potent array of bronchoconstrictive mediators. LÄS MER

  5. 4. Mast cells and their progenitors in respiratory diseases : Understanding their connection to lung function and airway inflammation

    Författare :P. Abigail Alvarado-Vazquez; Jenny Hallgren; Arne Egesten; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mast cells; mast cell progenitors; pulmonary function test; allergic airway inflammation; experimental asthma model; Immunologi; Immunology;

    Sammanfattning : Mast cells are rare immune cells involved in allergic diseases, including asthma. These cells are derived from mast cell progenitors (MCps) that migrate to the peripheral tissues via the blood in response to allergic or non-allergic stimuli. LÄS MER

  7. 5. New Aspects of Mast Cell Progenitors in Health and Disease

    Författare :Maya Salomonsson; Jenny Hallgren Martinsson; Silvia Bulfone-Paus; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Mast cells; Mast cell progenitor; Lung function; Bone marrow; Blood; Activation; Chemotactic receptors;

    Sammanfattning : Mast cells are tissue-resident immune cells that are well known for their involvement in asthma and allergy. They originate in the fetal yolk sac, or in the bone marrow. From the bone marrow, they are released as immature progenitors that are transported via the blood circulation to the peripheral tissue, where they mature. LÄS MER