Sökning: "mRNA decay"

Visar resultat 6 - 10 av 21 avhandlingar innehållade orden mRNA decay.

  1. 6. Membrane Stress and the Role of GYF Domain Proteins

    Författare :Alexander Georgiev; Åke Wieslander; Hana Sychrova; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; SYH1; SMY2; YPT6; RIC1; MYR1; processing bodies; vesicular trafficking; lipid bilayer; budding yeast; GYF; membrane stress; mRNA decay; Saccharomyces cerevisiae; Biochemistry; Biokemi; biokemi; Biochemistry;

    Sammanfattning : Intracellular membrane trafficking is regulated by a large number of protein complexes and lipids. Blocking of trafficking disrupts normal membrane dynamics and causes membrane stress. LÄS MER

  3. 7. Post-transcriptional regulation by RNases in Streptococcus pyogenes

    Författare :Anne-Laure Lécrivain; Emmanuelle Charpentier; Bernt Eric Uhlin; Tracy Nissan; Ciarán Condon; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Post-transcriptional regulation; mRNA decay; RNA sequencing; RNase Y; RNase III; YhaM; PNPase; RNase R; RNase J1; Streptococcus pyogenes.; molekylärbiologi; Molecular Biology;

    Sammanfattning : Ribonucleases (RNases) are proteins that adjust cellular RNA levels by processing RNA transcripts, leading to their stabilization or degradation. RNases are grouped based on their ability to cleave the transcript internally (endoRNases) or degrade the transcript starting from the ends (exoRNases). LÄS MER

  4. 8. Microarray-based investigation of genome and transcriptome organisation in the archaeon sulfolobus

    Författare :Anders Andersson; Joakim Lundeberg; Per Sunnerhagen; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Biotechnology; microarray; Sulfolobus; gene expression; archaea; mRNA decay; genome evolution; Bioteknik; Bioengineering; Bioteknik;

    Sammanfattning : .... LÄS MER

  5. 9. Simplified Nonsense: New Methods for Interrogating NMD

    Författare :Hanna Alalam; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; mRNA degradation; metabolic labeling; nonsense-mediated decay; Major protease; SARS-CoV-2;

    Sammanfattning : Nonsense mediated decay (NMD) is a pathway that regulates RNA turnover. Since its discovery, this pathway has been implicated in a variety of cellular processes ranging from differentiation to the restriction of viral replication. LÄS MER

  7. 10. Exploring the interplay between mRNA degradation and ribosome dynamics using high-throughput sequencing

    Författare :Yujie Zhang; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Regulation of gene expression in response to fluctuating environments is essential for cellular survival. This regulation is multi-faceted, with mRNA abundance determined by both synthesis and decay. mRNA decay regulates transcript abundance, enabling swift transcriptomic adaptations. LÄS MER