Sökning: "Per Sunnerhagen"

Visar resultat 1 - 5 av 6 avhandlingar innehållade orden Per Sunnerhagen.

  1. 1. Microarray-based investigation of genome and transcriptome organisation in the archaeon sulfolobus

    Författare :Anders Andersson; Joakim Lundeberg; Per Sunnerhagen; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Biotechnology; microarray; Sulfolobus; gene expression; archaea; mRNA decay; genome evolution; Bioteknik; Bioengineering; Bioteknik;

    Sammanfattning : .... LÄS MER

  3. 2. Chromatin Dynamics in the Fission Yeast, Schizosaccharomyces pombe

    Författare :Carolina Kristell; Pernilla Bjerling; Per Sunnerhagen; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Chromatin; Gene induction; Silencing; Subnuclear localization; Stress; Molecular biology; Molekylärbiologi; Molekylär genetik; Molecular Genetics;

    Sammanfattning : In the eukaryotic cell nucleus, spatial organization and dynamics of the genome is important in the regulation of gene expression. This thesis describes the use of the fission yeast, Schizosaccharomyces pombe, to study chromatin regulation and dynamics. We used nitrogen starvation to induce transcription of genes in fission yeast cells. LÄS MER

  4. 3. mRNA degradation factors as regulators of the gene expression in Saccharomyces cerevisiae

    Författare :Mridula Muppavarapu; Tracy Nissan; Per Sunnerhagen; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mRNA decapping; mRNA degradation; Pat1; Edc3; Lsm4; Lsm1-7; P bodies; Dcp2; Transcription; Ribosome biogenesis; Exosome.; molekylärbiologi; Molecular Biology;

    Sammanfattning : Messenger RNA degradation is crucial for the regulation of eukaryotic gene expression. It not only modulates the basal mRNA levels but also functions as a quality control system, thereby controlling the availability of mRNA for protein synthesis. LÄS MER

  5. 4. Insights into the roles of the essential Pfh1 DNA helicase in the nuclear and mitochondrial genomes

    Författare :Parham Pourbozorgi Langroudi; Nasim Sabouri; Anders Hofer; Per Sunnerhagen; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; G4; genome integrity; Pfh1; Top1; helicase; topoisomerase; replication; transcription;

    Sammanfattning : Eukaryotic cells have two sets of genomes, the nuclear and mitochondrial, and both need to be accurately maintained. Also, the rate of transcription must be precisely regulated in these genomes. However, there are many natural barriers that dysregulate these processes. LÄS MER

  7. 5. Structural and Functional Studies on Evolutionary Repurposing of H-box/NC-proteins : From Host Factor to Virus Protein

    Författare :Anna Wehlin; Eleonore von Castelmur; Per Hammarström; Maria Sunnerhagen; Lars-Göran Mårtensson; Lars-Anders Carlson; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : The Picornaviridae are a large family of biomedically important viruses causing diseases such as the common cold, hepatitis A and polio in humans and foot-and-mouth disease in cattle. These diseases have great impact on people’s everyday life and cause economical losses all around the world. To date, no antiviral treatments are available. LÄS MER