Sökning: "metabolic labeling"

Visar resultat 1 - 5 av 23 avhandlingar innehållade orden metabolic labeling.

  1. 1. Plant Membrane Proteomics - using isolated membranes and proteins to compare and quantify subproteomes

    Författare :Katja Bernfur; Biokemi och Strukturbiologi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Mass spectrometry; quantification; proteomics; metabolic labeling; plasma membrane;

    Sammanfattning : Membrane proteins are particularly important to characterize, since they are involved in cellular processes of utmost importance in control and regulation of cells, such as transport across membranes, signal transduction and photosynthesis. The word "proteome" means all proteins expressed by a e.g. LÄS MER

  3. 2. Simplified Nonsense: New Methods for Interrogating NMD

    Författare :Hanna Alalam; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; mRNA degradation; metabolic labeling; nonsense-mediated decay; Major protease; SARS-CoV-2;

    Sammanfattning : Nonsense mediated decay (NMD) is a pathway that regulates RNA turnover. Since its discovery, this pathway has been implicated in a variety of cellular processes ranging from differentiation to the restriction of viral replication. LÄS MER

  4. 3. Mass spectrometry based proteomic strategies applied in the study of central nervous system derived cells

    Författare :Annika Thorsell; Göteborgs universitet; []
    Nyckelord :proteomics; mass spectrometry; protein identification; protein quantitation; fractionation;

    Sammanfattning : This thesis focuses on evaluation, improvement and development of mass spectrometry based proteomic strategies for identification and quantitation of proteins. Development of such strategies is important to achieve a better understanding of regulatory mechanisms of individual cell types, both during normal development and during the onset and progression of diseases. LÄS MER

  5. 4. Immunocytochemical studies of excitatory amino acid neurotransmitters and transporters in the spinal cord and nucleus submedius

    Författare :Stefan Persson; Neurofysiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neuropsykologi; neurophysiology; neuropsychology; Neurology; VGLUT2; VGLUT1; pain; somatosensory; thalamus; immunogold; glutamate; aspartate; dorsal horn; excitatory amino acids; spinal cord; neurofysiologi; Neurologi;

    Sammanfattning : The amino acid glutamate is today regarded as the main fast excitatory neurotransmitter in the central nervous system and a large body of evidence support that glutamate serves as a neurotransmitter in primary afferent terminals in the spinal cord. Previous evidence also suggests that the closely related amino acid aspartate may serve a similar role in some primary afferent terminals. LÄS MER

  7. 5. Cell Therapy in lntervertebral Disc Degeneration

    Författare :Papadimitriou Nicolaos; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Low back pain; Mesenchymal stromal cell; Intervertebral disc; Intervertebral disc degeneration; Degenerative disc disease; Cell therapy;

    Sammanfattning : Background: Chronic low back pain (LBP) is the leading cause of disability worldwide. Intervertebral disc degeneration (IDD) is central in the pathogenesis. The injection of bone marrow-derived mesenchymal stromal cells (BM-MSCs) into degenerate intervertebral discs (IVDs) has been proposed as an alternative therapy. LÄS MER