Sökning: "knowledge discovery"
Visar resultat 21 - 25 av 199 avhandlingar innehållade orden knowledge discovery.
21. Lära för skrivundervisning : En studie om skrivdidaktisk kunskap i ämneslärarutbildningen och läraryrket
Sammanfattning : Syftet med avhandlingen är att undersöka hur och under vilka villkor som svensklärares kunskap om skrivundervisning växer fram i och efter lärarutbildningen.I en delstudie analyseras hur skrivande, skrivutveckling och skrivundervisning framställs och förmedlas som kunskapsområden i kursplaner som beskriver ämnesteoretiska och ämnesdidaktiska kurser i ämneslärarutbildningen i svenska. LÄS MER
22. Machine Learning Enabled Functional Discovery in Yeast Systems Biology
Sammanfattning : Saccharomyces cerevisiae is a well-studied organism, yet roughly 20 percent of its proteins remain poorly characterized. Recent studies also seem to indicate that the pace of functional discovery is slow. LÄS MER
23. Characterization of HCV Protease Inhibitors : Inhibition and Interaction Studies with Applications for Drug Discovery
Sammanfattning : In this thesis, different approaches based on inhibition and interactions studies, have been used to characterize inhibitors of the non-structural protein 3 (NS3) from the hepatitis C virus (HCV). This involves identification of enzyme inhibitory effects and characterization of interaction mechanisms and kinetics, as well as effects on replication in a cell based system and serum protein binding. LÄS MER
24. Drug discovery targeting non-amyloid pathways in Alzheimer’s disease
Sammanfattning : Alzheimer’s disease (AD) is the most common form of dementia with almost 50 million people affected and unfortunately, no cure or treatment to halt the disease progression is available. In the hereditary forms of AD, an overproduction of amyloid β (Aβ) and the Aβ plaque formation are the basis for the amyloid hypothesis of AD, while several additional factors seem to influence the likelihood to develop sporadic forms of AD. LÄS MER
25. Data-driven and production-oriented tendering design using artificial intelligence
Sammanfattning : Construction projects are facing an increase in requirements since the projects are getting larger, more technology is integrated into the buildings, and new sustainability and CO2 equivalent emissions requirements are introduced. As a result, requirement management quickly gets overwhelming, and instead of having systematic requirement management, the construction industry tends to trust craftsmanship. LÄS MER