Sökning: "ion channel receptor"
Visar resultat 21 - 25 av 65 avhandlingar innehållade orden ion channel receptor.
21. The Biophysics of Na+,K+-ATPase in neuronal health and disease
Sammanfattning : Na+,K+-ATPase is one of the most important proteins in the mammalian cell. It creates sodium and potassium gradients which are fundamental for the membrane potential and sodium-dependent secondary active transport. LÄS MER
22. Chloride Channels and Brown Fat Cells
Sammanfattning : Chloride ion channels are macromolecular pores providing for passage of chloride ions (and certain other inorganic and organic anions) through the cell membrane, down their electrochemical gradients. Chloride channels are differentially expressed in various cells, to best suit specific cellular activities. LÄS MER
23. Techniques to manipulate the environment around and inside single cells
Sammanfattning : Several methods for extending the functionality of a commercially available microfluidic system have been developed to allow for the manipulation of the extracellular and intracellular environments. The microfluidic system generates a chemically patterned laminar flow in an open volume. LÄS MER
24. Physiology and Pharmacology of GABAA receptors: The Brakes in the Brain
Sammanfattning : Inhibitory neurotransmission in the brain is mostly mediated by gamma-aminobutyric acid type A (GABAA) receptors. These receptors are involved in both phasic inhibition (point-to-point inhibition, synaptic transmission) and tonic inhibition (diffuse form of inhibition, brain homeostasis). LÄS MER
25. Allosteric modulation of pentameric ligand-gated ion channels by general anesthetics
Sammanfattning : Pentameric ligand-gated ion channels (pLGICs) are key components of fast synaptic transmission and are targets of neuroactive drugs such as benzodiazepines, alcohol and muscle relaxants. Although early theories of general anesthesia suggested non-specific lipid interaction as the mechanism of anesthetic action, it has now become evident that they too bind to pLGICs. LÄS MER