Sökning: "Chloride channel"

Visar resultat 1 - 5 av 38 avhandlingar innehållade orden Chloride channel.

  1. 1. Ion channel control of phasic insulin secretion

    Författare :Xingjun Jing; Diabetes - öpatofysiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; phasic insulin secretion; Diabetes; pancreatic β-cells; ClC chloride channel; exocytosis; CaV channel;

    Sammanfattning : Glucose-stimulated insulin secretion exhibits a biphasic pattern. The mechanism underling biphasic insulin secretion is not fully understood, but consensus exists that an elevation in [Ca2+]i is required for both first- and second-phase insulin secretion. LÄS MER

  3. 2. Chloride Channels and Brown Fat Cells

    Författare :Victor Sabanov; Jan Nedergaard; Bernd Nilius; Stockholms universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Chloride channel; BAPTA; EGTA; Ca; Animal physiology; Zoofysiologi;

    Sammanfattning : Chloride ion channels are macromolecular pores providing for passage of chloride ions (and certain other inorganic and organic anions) through the cell membrane, down their electrochemical gradients. Chloride channels are differentially expressed in various cells, to best suit specific cellular activities. LÄS MER

  4. 3. Regulation of chloride secretion in HT29 cells studied by X-ray microanalysis

    Författare :Wei Zhang; Uppsala universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Anatomy; epithelium; chloride channel; HT29 cells; ion transport; volume; X-ray microanalysis; G-protein coupled receptors; α2-adrenoceptors; purinoceptors; muscarinic receptors; Anatomi; Anatomy; Anatomi; Human Anatomy; anatomi;

    Sammanfattning : Several aspects of Cl- secretion in epithelial cells were investigated. Methods to prepare cultured cellsfor X-ray microanalysis, in order to study volume-regulating chloride transport were evaluated. LÄS MER

  5. 4. Chloride transport and inflammation in cystic fibrosis airways

    Författare :Georgia Varelogianni; Godfried Roomans; Marie Johannesson; Ólafur Baldersson; Örebro universitet; []
    Nyckelord :Cystic fibrosis; CFTR; chloride efflux; N-acetylcysteine; ambroxol; duramycin; Nod-like receptors; cytokines; Medicin; Medicine;

    Sammanfattning : Cystic fibrosis (CF) is one of the most common lethal, autosomal recessive inherited diseases among Caucasians. It is caused by a mutation in the cystic fibrosis transmembrane conductance regulator (CFTR), a chloride channel activated by cyclic AMP. LÄS MER

  7. 5. Molecular regulation of epithelial tube size

    Författare :Erika Tång Hallbäck; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Nyckelord :Drosophila; tube shape; trachea; chitin; luminal matrix; epithelial tubes; morphogenesis; chloride channel; subapical actin;

    Sammanfattning : In nature, epithelial tubes are vital structures in organ design and are required for transport of gases and liquids in organs, such as the vascular system, the vertebrate lung and the kidneys. The tubular epithelium is single layered, but is often reinforced by layers of muscular support. LÄS MER