Sökning: "Chloride channel"
Visar resultat 1 - 5 av 38 avhandlingar innehållade orden Chloride channel.
1. Ion channel control of phasic insulin secretion
Sammanfattning : Glucose-stimulated insulin secretion exhibits a biphasic pattern. The mechanism underling biphasic insulin secretion is not fully understood, but consensus exists that an elevation in [Ca2+]i is required for both first- and second-phase insulin secretion. LÄS MER
2. Chloride Channels and Brown Fat Cells
Sammanfattning : Chloride ion channels are macromolecular pores providing for passage of chloride ions (and certain other inorganic and organic anions) through the cell membrane, down their electrochemical gradients. Chloride channels are differentially expressed in various cells, to best suit specific cellular activities. LÄS MER
3. Chloride transport and inflammation in cystic fibrosis airways
Sammanfattning : Cystic fibrosis (CF) is one of the most common lethal, autosomal recessive inherited diseases among Caucasians. It is caused by a mutation in the cystic fibrosis transmembrane conductance regulator (CFTR), a chloride channel activated by cyclic AMP. LÄS MER
4. Molecular regulation of epithelial tube size
Sammanfattning : In nature, epithelial tubes are vital structures in organ design and are required for transport of gases and liquids in organs, such as the vascular system, the vertebrate lung and the kidneys. The tubular epithelium is single layered, but is often reinforced by layers of muscular support. LÄS MER
5. Functional Aspects of Epithelia in Cystic Fibrosis and Asthma
Sammanfattning : The cystic fibrosis transmembrane conductance regulator (CFTR), a cAMP activated chloride channel in the apical membrane of epithelial cells, is defective in patients with cystic fibrosis (CF). Research efforts are focused on chloride channel function in order to find a cure for the disease. LÄS MER