Sökning: "ion channels"

Visar resultat 1 - 5 av 182 avhandlingar innehållade orden ion channels.

  1. 1. Ion Tracks for Micro- and Nanofabrication From Single Channels to Superhydrophobic Surfaces

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Reimar Spohr; Uppsala universitet.; [2010]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Ion track; single ion; real time; phase detection; conductometric cell; conductometry; electro replication; microtechnology; nanotechnology; surfactant; self organization; GMR; magnetic; sensor technology; hydrophobic; tilted texture.; NATURAL SCIENCES Physics; NATURVETENSKAP Fysik; Materialvetenskap; Materials Science;

    Sammanfattning : A method is described for preset-count irradiations between 1 and 100 ions singling-out individual ions from an ion beam with more than a billion ions arriving per second. The ion tracks are etched in a conductometric system with real-time evaluation of the acquired data. The etch process can be interrupted when reaching a preset channel diameter. LÄS MER

  2. 2. Modeling of voltage-gated ion channels

    Detta är en avhandling från Stockholm : Department of Biochemistry and Biophysics. Stockholm University

    Författare :Pär Bjelkmar; Stockholms universitet.; [2011]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Molecular modeling; Molecular dynamics; Voltage-gating; Ion channels; Protein structure prediction; NATURAL SCIENCES Chemistry; NATURVETENSKAP Kemi; biokemi; inriktning teoretisk kemi; Biochemistry with Emphasis on Theoretical Chemistry;

    Sammanfattning : The recent determination of several crystal structures of voltage-gated ion channels has catalyzed computational efforts of studying these remarkable molecular machines that are able to conduct ions across biological membranes at extremely high rates without compromising the ion selectivity. Starting from the open crystal structures, we have studied the gating mechanism of these channels by molecular modeling techniques. LÄS MER

  3. 3. Dendritic and axonal ion channels supporting neuronal integration From pyramidal neurons to peripheral nociceptors

    Detta är en avhandling från Stockholm : KTH Royal Institute of Technology

    Författare :Marcus Petersson; KTH.; [2012]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; ion channels; computational modeling; simulations; dendrites; axons; TRP; hippocampus; C-fiber nociceptors; pain;

    Sammanfattning : The nervous system, including the brain, is a complex network with billions of complex neurons. Ion channels mediate the electrical signals that neurons use to integrate input and produce appropriate output, and could thus be thought of as key instruments in the neuronal orchestra. LÄS MER

  4. 4. The interplay of ions in the stimulation of the pancreatic -cell

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Michael Eberhardson; Uppsala universitet.; [1999]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cell biology; diabetes; pancreatic β-cells; cytoplasmic calcium; oscillations; glucose; tetrodotoxin; tolbutamide; veratridine; tetraethylammonium; quinine; cesium; H2DIDS; furosemide; transients; microfluorometry; fura-2; MQAE; calcium channels; potassium channels; sodium channels; chloride channels; Cellbiologi; MEDICINE Morphology; cell biology; pathology Cell biology; MEDICIN Morfologi; cellbiologi; patologi Cellbiologi; medicinsk cellbiologi; Medical Cell Biology;

    Sammanfattning : Glucose stimulation of insulin release is mediated by depolarisation of the pancreatic β-cells with accompanying entry of Ca2+ through voltage-dependent channels. An important feature of the glucose-induced depolarisation is its rhythmicity causing oscillations of the cytoplasmic Ca2+ concentration ([Ca2+]i), which trigger pulsatile release of insulin. LÄS MER

  5. 5. Studies of individual pancreatic -cells : Electrophysiological analysis of rhythmic behaviour and development of new techniques

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Staffan Dryselius; Uppsala universitet.; [1999]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cell biology; Diabetes; pancreatic beta-cells; insulin release; signal transduction; cytoplasmic calcium; oscillations; patch clamp; ATP-regulated potassium channels; voltage-dependent calcium channels; metabolism; calcium ion; strontium ion; manganese ion; wavelets; de-noising; pattern recognition; superfusion; solution changes; microscopic labelling; Cellbiologi; MEDICINE Morphology; cell biology; pathology Cell biology; MEDICIN Morfologi; cellbiologi; patologi Cellbiologi; medicinsk cellbiologi; Medical Cell Biology;

    Sammanfattning : The insulin concentration in blood varies periodically, which is believed to prevent down-regulation of the hormone receptors. Loss of the regular insulin oscillations is considered to be an early sign of developing diabetes. LÄS MER