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Visar resultat 1 - 5 av 23 avhandlingar som matchar ovanstående sökkriterier.
1. Replication Dynamics in the DNA Damage Response
Sammanfattning : Faithful DNA replication is essential and the induction of replication stress may have profound effects on genomic integrity. This is demonstrated by the formation of DNA double strand breaks (DSBs), considered to be the most toxic DNA lesions, at stalled replication forks. LÄS MER
2. Gene Expression Patterns in a Rat Model of Human Endometrial Adenocarcinoma
Sammanfattning : Endometrial cancer develops from the endometrium of the uterus and is the most common pelvic malignancy diagnosed in women in the western society. Similar to all cancer diseases, endometrial cancer is a disorder that results from complex patterns of genetic and epigenetic alterations involved in the malignant transformation. LÄS MER
3. Microarray Based Gene Expression Analysis in Cancer Research
Sammanfattning : Biotechnological inventions during the 20th century have resulted in a wide range of approaches for explorations in the functional genomics field. Microarray technology is one of the recent advances which have provided us with snapshots of which genes are expressed in cells of various tissues and diseases. LÄS MER
4. Molecular architecture of meiotic chromosomes
Sammanfattning : Faithful chromosome segregation at each cell division is essential as the formation of cells with an abnormal number of chromosomes (aneuploid cells) can result in infertility, developmental defects or cancer. Aneuploidy occurs in approximately 20% of all conceptions, causing infertility and embryo death. LÄS MER
5. Acute pancreatitis, from local defense to remote organ injury
Sammanfattning : Acute pancreatitis (AP) is an inflammatory disease of the pancreas. Acute abdominal pain is the most common symptom. Pancreatic injury is mild in 80% of patients, who recover without complications. The remaining patients have a severe disease with local and systemic complications such as acute lung injury (ALI). LÄS MER