Sökning: "complex disease"
Visar resultat 1 - 5 av 1348 avhandlingar innehållade orden complex disease.
Sammanfattning : To find true genetic associations in complex diseases, such as allergic rhinitis and chronic rhinosinusitis, is a difficult task. Both are polygenetic diseases where it is believed that genetic variation in several genes make up their phenotypes. LÄS MER
Sammanfattning : The complex disease investigations presented in this thesis aimed to provide new information regarding underlying genetics by using targeted sequencing and ethnically homogeneous cohorts. This work moved past current methodologies and addressed data stratification issues, that might have been hindering new findings. LÄS MER
3. Psoriatic arthritis: a complex disease : analyses on genetic and serological biomarkers and of comorbidity
Sammanfattning : Psoriatic Arthritis (PsA) is a heterogonous inflammatory arthritis associated with psoriasis. The disease leads to inflammation of peripheral joints, axial skeleton and/or enthesites, and can result in severe destruction of affected joints. LÄS MER
Sammanfattning : Complex diseases are caused by the activities of many genes acting in concert with environmental factors. A major challenge facing human genetic research is to unravel the genetic factors behind complex disorders. LÄS MER
5. Geospatial Knowledge Discovery using Volunteered Geographic Information : a Complex System Perspective
Sammanfattning : The continuous progression of urbanization has resulted in an increasing number of people living in cities or towns. In parallel, advancements in technologies, such as the Internet, telecommunications, and transportation, have allowed for better connectivity among people. LÄS MER