Sökning: "adrenocortical tumour"

Visar resultat 1 - 5 av 7 avhandlingar innehållade orden adrenocortical tumour.

  1. 1. Insights into the transcriptomic profiling of adrenocortical tumors

    Författare :David Velázquez-Fernández; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Adrenocortical tumours;

    Sammanfattning : An adrenocortical tumour (ACT) can be detected in up to 5% of the population older than 50 years of age. The frequency increases with age. More ACTs are being detected in parallel with the increased use of high-resolution imaging. LÄS MER

  3. 2. Microarray Based Gene Expression Analysis in Cancer Research

    Författare :Cecilia Laurell; Joakim Lundberg; Peter Nilsson; Karin Dahlman-Wright; KTH; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; adrenocortical tumour; apoptosis; cancer; classification; gene expression; microarray; p53; RNA amplification; Molecular biology; Molekylärbiologi;

    Sammanfattning : Biotechnological inventions during the 20th century have resulted in a wide range of approaches for explorations in the functional genomics field. Microarray technology is one of the recent advances which have provided us with snapshots of which genes are expressed in cells of various tissues and diseases. LÄS MER

  4. 3. Functional and diagnostic aspects on adrenocortical adenoma

    Författare :Ulla Enberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Adrenocortical tumours are frequently detected due to increased use of imaging techniques like computed tomography, magnetic resonance imaging or ultrasound. The majority of the patients have tumours that do not have any overproduction of hormone. LÄS MER

  5. 4. New Insights in Adrenal Tumourigenesis

    Författare :Rajani Maharjan; Peyman Björklund; Michaela Luconi; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cortisol producing adenomas; adrenocortical carcinomas; mutation; heterogeneity; PRKACA; TERT; CTNNB1; Molekylär genetik; Molecular Genetics;

    Sammanfattning : Unilateral cortisol producing adenoma (CPA) is the most common cause of ACTH-independent Cushing’s syndrome and is surgically curable. On the other hand, adrenocortical carcinomas (ACCs) are rare and aggressive tumours. LÄS MER

  7. 5. Clinical aspects of Adrenalectomy

    Författare :Lo Hallin Thompson; Lund Kirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Adrenalectomy; Adrenal tumour; Adrenal surgery; Adrenal incidentaloma; Health Related Quality of Life; Quality register;

    Sammanfattning : Annual rates of adrenalectomy have doubled in the last 20 years as a consequence of increased detection of adrenal incidentalomas, improved biochemical diagnosis, genetic screening, and minimally invasive surgical techniques. Most adrenal incidentalomas are benign non-functional adrenocortical adenomas. LÄS MER