Sökning: "Chromosome architecture"
Visar resultat 1 - 5 av 13 avhandlingar innehållade orden Chromosome architecture.
Sammanfattning : Faithful chromosome segregation at each cell division is essential as the formation of cells with an abnormal number of chromosomes (aneuploid cells) can result in infertility, developmental defects or cancer. Aneuploidy occurs in approximately 20% of all conceptions, causing infertility and embryo death. LÄS MER
Sammanfattning : Phenotypic differences between the sexes evolve largely because selection favours a different complement of traits in either sex. Theory suggests that, despite its frequency, sexual dimorphism should be generally constrained from evolving because the sexes share much of their genome. LÄS MER
3. Coiled coil Cytoskeleton in Bacterial Cell Architecture : Studies of Growth and Development in Streptomyces
Sammanfattning : Bacterial cytoskeleton is an exciting and relatively new field of research. Recent findings have proven that microbes are well-organized and neatly structured organisms. LÄS MER
Sammanfattning : The thesis explores the dynamic features and functions of chromatin crosstalk in the 3D nucleus space, with a focus on the regulation of chromatin transitions. In Paper I we employed the circular chromosome conformation capture assay (4C) and Chromatin in situ Proximity (ChrISP) technique to uncover an inter-chromosomal chromatin fiber interactome comprising both transcriptionally active circadian genes and repressed lamina-associated domains (LADs). LÄS MER
5. Evolutionary dynamics of migration and breeding in wild birds: genetic architecture, sexual conflicts and evolutionary constraints
Sammanfattning : Our knowledge of the evolutionary potential of traits involved in different selective episodes, especially in natural populations, is still limited. This is true for questions such as the genetic basis and inheritance of traits, how natural and sexual selection acts on them, and how selective conflicts influence the evolutionary response to selection. LÄS MER