Sökning: "cytokin"
Visar resultat 6 - 10 av 19 avhandlingar innehållade ordet cytokin.
6. Immunoregulation in an experimental model of allergic asthma
Sammanfattning : In allergic asthma the immune response to antigen is inappropriate, leading to an inflammatory process in the respiratory mucosa. To further elucidate immunological mechanisms involved in the development of such inflammation, control mice and mice deficient in selected cell types or proteins, were used in experimental models of allergic asthma and anaphylaxis. LÄS MER
7. Activation of human B cells with the Moraxella catarrhalis IgD-binding protein MID
Sammanfattning : Moraxella catarrhalis is a respiratory tract pathogen that causes significant health problems, including acute otitis media in children, lower respiratory tract infections in adults and the elderly and sinusitis in both children and adults. The interest in M. LÄS MER
8. Immune responses to lipopolysaccharide in relation to allergic disease : a TLR4 gene polymorphism and endotoxin exposure
Sammanfattning : Background: Allergic diseases have increased during the last decades, particularly in affluent countries, possibly due to a reduced and/or altered microbial exposure during infancy. Activation of the immune system by microbes early in life is probably required for accurate maturation of the immune system and tolerance development. LÄS MER
9. Activation of murine cytotoxic cells with interelukin-2 and the bacterial superantigen staphylococcal entertoxin A
Sammanfattning : Natural killer (NK) cells and T lymphocytes are the major effector cells that can recognize and kill tumor cells. NK cells have a constitutive cytotoxic activity and kill a wide spectrum of tumor cells while T cells recognize specific tumor antigens and need to be activated through their TCR to differentiate into cytotoxic T lymphocyte (CTL) killers or T helper cells. LÄS MER
10. Systemic and Local Inflammatory Mediator Response to Major Surgery
Sammanfattning : Cell-signalling via cytokines modulates the local response to surgical trauma, directs the immunologic response and initiates the healing process. Surgical trauma induces a systemic cytokine response and a down-regulation of the antigen presentation capacity of monocytes (HLA-DR expression), which is associated with a poor prognosis if pronounced. LÄS MER