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Visar resultat 16 - 20 av 21 avhandlingar som matchar ovanstående sökkriterier.

1. 16. Adenovirus for Cancer Therapy : With a Focus on its Surface Modification

   Författare :Di Yu; Magnus Essand; Dirk Nettelbeck; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Adenovirus; cancer; therapy; neuroblastoma; neuroendocrine; modification; Tat; PTD; cell penetrating peptide; Helicobacter pylori; NAP; Biology with specialization in Molecular Biology; Biologi med inriktning mot molekylärbiologi; Klinisk virologi; Clinical Virology; Medical Virology; Medicinsk virologi; Molekylär medicin; Molecular Medicine; Molekylär bioteknik; Molecular Biotechnology;

   Sammanfattning : Adenovirus serotype 5 (Ad5) is widely used as an oncolytic agent for cancer therapy. However, its infectivity is highly dependent on the expression level of coxsackievirus-adenovirus receptor (CAR) on the surface of tumor cells. LÄS MER

3. 17. Capsid protein functions of enteric human adenoviruses

   Författare :Anandi Rajan; Niklas Arnberg; Stefan Schwartz; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Adenovirus; gastroenteritis; capsid proteins; receptor; integrins; heparan sulfate; sialic acid;

   Sammanfattning : Human adenoviruses (HAdVs) cause respiratory illnesses, epidemic conjunctivitis and infantile gastroenteritis. HAdV types 40 and 41 cause enteric infections in infants worldwide. HAdVs use various receptors for attachment onto different host cells. LÄS MER

4. 18. Interactions between enteroviruses and the host : implications for type 1 diabetes

   Författare :Pär Larsson; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Type 1 diabetes (T1D) is a disease that results after a selective destruction of the insulin-producing β-cells in the pancreas. The lack of β-cells renders T1D patients completely unable to synthesize and secrete insulin, which leads to a life-long need of exogenous insulin for survival. LÄS MER

5. 19. Cellular receptors for viruses with ocular tropism

   Författare :Emma C Nilsson; Niklas Arnberg; Eric J Kremer; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Adenovirus; picornavirus; receptors; antivirals; Virology; Virologi; molekylärbiologi; Molecular Biology; Infectious Diseases; infektionssjukdomar; mikrobiologi; Microbiology;

   Sammanfattning : Several viruses from different virus families are known to cause ocular infections, e.g. members of the Adenoviridae, Picornaviridae and the Herpesviridae families. These infections are spread by contact and in the case of adenoviruses (Ads) and picornaviruses they are also highly contagious. LÄS MER

7. 20. Biochemical and structural studies of proteins supporting the genome replication of enteroviruses and Giardia intestinalis

   Författare :Kasturika Shankar; Lars-Anders Carlson; Daniel Hurdiss; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Biochemistry; Structural Biology; Membrane reconstitution; Infectious diseases; Virus; Protozoa; Infectious Diseases; infektionssjukdomar; medicinsk biokemi; Medical Biochemistry;

   Sammanfattning : The Enterovirus genus of the Picornaviridae family includes non-enveloped, positive-sense single-stranded RNA (ssRNA) viruses. This genus of viruses causes many diseases such as poliomyelitis by poliovirus (PV), cardiomyopathy by coxsackievirus B3 (CVB3), common cold by rhinoviruses (RVs) and meningitis by Enterovirus 71 (EV 71). The 7. LÄS MER