Sökning: "monoamine metabolites"

Visar resultat 1 - 5 av 19 avhandlingar innehållade orden monoamine metabolites.

  1. 1. Self-rated aggression. Psychobiological aspects and gender issues in medical-psychiatric practice

    Författare :Helena Prochazka; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; self-rated aggression; questionnaire; AQ-RSV; physical aggression; verbal aggression; hostility; anger; monoamine metabolites; platelet MAO activity; testosterone; fibromyalgia; depression; gender; sex; female;

    Sammanfattning : Background. The complexities of human aggression are of vital research interest in numerous scientific disciplines. In medical research, aggression is generally studied by means of self- or observer-rated inventories, clinical observations, or neurobiological research. Objectives. LÄS MER

  3. 2. Pharmacokinetics of probenecid with emphasis on its induced accumulation of central monoamine metabolites

    Författare :Britt-Marie Emanuelsson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; PHARMACY; FARMACI;

    Sammanfattning : .... LÄS MER

  4. 3. Molecular genetic studies on cerebrospinal fluid monoamine metabolites in psychotic patients and healthy individuals

    Författare :Dimitrios Andreou; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Cerebrospinal fluid CSF ;

    Sammanfattning : Dopamine, serotonin and noradrenaline are the major monoamines in the human central nervous system (CNS) and following their basic pathways they are degraded to their major metabolites homovanillic acid (HVA), 5-hydroxyindoleacetic acid (5-HIAA) and 3-methoxy-4-hydroxyphenylglycol (MHPG), respectively. The cerebrospinal fluid (CSF) concentrations of the three monoamine metabolites (MM) are considered to reflect the monoamine turnover rates in the CNS, are under genetic influence and have been associated with schizophrenia. LÄS MER

  5. 4. Season of birth in suicidology : neurobiological and epidemiological studies

    Författare :Jayanti Chotai; Hans Ågren; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; season of birth; CSF monoamine metabolites; suicide method; borderline;

    Sammanfattning : Background: Several neuropsychiatrie disorders have shown season of birth associations. Low cerebrospinal fluid (CSF) levels of the serotonin metabolite 5-HIAA and the dopamine metabolite HVA have been associated with suicidal behaviour, impulsivity, and aggression. LÄS MER

  7. 5. Genetic aspects on schizophrenia and cerebrospinal fluid monoamine metabolites : focus on association studies with candidate genes

    Författare :Erik Jönsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :association study; schizophrenia; DNA polymorphisms; dopamine receptors DRD2; DRD3; DRD4 ; tyrosine hydroxylase; tryptophan hydroxylase; catechol-O-methyltransferase; neurotrophin-3; ciliary neurotrophic factor; healthy subjects; cerebrospinal fluid;

    Sammanfattning : Schizophrenia is a syndrome with psychotic symptoms. The pathogenesis of schizophrenia most likely reflects brain abnormalities and heritable components are present. The principal objective of the present thesis was to investigate some possible genetic influences in the genesis or pathophysiology of schizophrenia. LÄS MER