Sökning: "chemokines"
Visar resultat 41 - 45 av 271 avhandlingar innehållade ordet chemokines.
41. On the cytotoxic and proinflammatory properties of eosinophils
Sammanfattning : Eosinophils are multi-functional leukocytes involved in the pathophysiology of inflammatory diseases such as asthma and inflammatory bowel disease. Participation in some neoplastic diseases and in the host defense against helminths has also been postulated. They are considered both good and bad, protecting or harming the host. LÄS MER
42. Innate and adaptive immunity in genital HSV-2 infection: Implications for vaccine development
Sammanfattning : Herpes simplex virus type 2 (HSV-2) is a sexually transmitted pathogen that infects the genital tract mucosa and is the most common case of genital ulcers in humans. Despite numerous studies, little is known about the mechanisms involved in immune protection and no anti-herpes vaccine has been developed to date. LÄS MER
43. Serine protease inhibitors in the upper and lower airways
Sammanfattning : Proteases and their inhibitors are implicated in the physiology and pathology of the airways. Protease inhibitors include those produced locally, such as secretory leukocyte protease inhibitor (SLPI), and those produced mainly by the liver that can reach the airways via passive diffusion, such as alpha1-antitrypsin (AAT). LÄS MER
44. Role of adhesion molecules and chemokines in TNF-alpha-induced leukocyte recruitment
Sammanfattning : Migration of leukocytes from the circulating blood into the extravascular tissue is a key component in inflammatory reactions. Leukocyte extravasation (rolling-activation-adhesion-transmigration) is strictly coordinated by adhesion molecules and chemokines expressed on cell surfaces and in tissues. LÄS MER
45. Studies on cytokines and chemokines in cerebrovascular diseases and experimental cerebral ischemia
Sammanfattning : Ischemic brain injury secondary to arterial occlusion, a major cause of stroke, is characterized by acute local inflammation, which involves the accumulation of polymorphonuclear neutrophils and other immune cells. Tissue damage resulting from ischemic stroke can be reduced in experimental animal models by blocking leukocyte accumulation. LÄS MER