Sökning: "cell-free system"

Visar resultat 21 - 25 av 49 avhandlingar innehållade orden cell-free system.

1. 21. Extracellular Matrix Based Materials for Tissue Engineering

   Författare :Cecilia Aulin; Jöns Hilborn; Tim Bowden; Laura Creemers; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Extracellular matrix; collagen synthesis; bioreactor; cell culture; bone morphogenetic protein-2; noggin; hyaluronan; cartilage; Medical technology; Medicinsk teknik; Molecular biology; Molekylärbiologi; Orthopaedics; Ortopedi; Transplantation surgery; Transplantationskirurgi; Biomaterials; Biomaterial; Morphology; cell biology; pathology; Morfologi; cellbiologi; patologi; Cell and molecular biology; Cell- och molekylärbiologi; Polymer chemistry; Polymerkemi; Materials chemistry; Materialkemi; cellforskning; Cell Research; materialvetenskap; Materials Science; medicinsk cellbiologi; Medical Cell Biology; ortopedi; Orthopaedics;

   Sammanfattning : The extracellular matrix is (ECM) is a network of large, structural proteins and polysaccharides, important for cellular behavior, tissue development and maintenance. Present thesis describes work exploring ECM as scaffolds for tissue engineering by manipulating cells cultured in vitro or by influencing ECM expression in vivo. LÄS MER

3. 22. Preclinical studies of ribozyme-mediated gene therapy for HIV-1

   Författare :Catharina Maijgren Steffensson; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :AIDS; antiretroviral; cis-cleavage; gene therapy; HAART; hairpin; hammerhead; HIV-1; in vitro; in vivo; ribozyme; RNA;

   Sammanfattning : Approximately 40 million people are infected with HIV-1 and AIDS is the number one cause of death in Africa as well as, the fourth leading cause of death globally. Patients in developed countries generally receive highly active antiretroviral therapy (HAART), even though the drugs are expensive and sometimes cause side-effects and treatment failure. LÄS MER

4. 23. Role of Heparan Sulfate Structure in FGF-Receptor Interactions and Signaling

   Författare :Nadja Jastrebova; Dorothe Spillmann; Ulf Lindahl; John T. Gallagher; Uppsala universitet; []
   Nyckelord :Biochemistry; heparan sulfate; oligosaccharide; fibroblast growth factor; fibroblast growth factor signaling; Biokemi;

   Sammanfattning : Heparan sulfate (HS) belongs to the glycosaminoglycan family of polysaccharides and is found attached to protein cores on cell surfaces and in the extracellular matrix. The HS backbone consists of alternating hexuronic acid and glucosamine units and undergoes a number of modification reactions creating HS chains with alternating highly and low modified domains, where high degree of modification correlates with high negative charge. LÄS MER

5. 24. Mechanisms of alloxan diabetogenicity

   Författare :Kjell Grankvist; Inge-Bert Täljedal; Umeå universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Alloxan; catalase; experimental diabetes; free radicals; islets of Langerhans; rubidium accumulation; superoxide dismutase; Trypan Blue;

   Sammanfattning : Suspensions of pancreatic islet cells from ob/ob-mice were incubated with Trypan Blue. Microscope photometry showed that apparently viable cells excluded the dye completely, whereas the nuclei of non-viable cells accumulated Trypan Blue by a saturable process. LÄS MER

7. 25. Systems with Massive Number of Antennas: Distributed Approaches

   Författare :Jesús Rodríguez Sánchez; Integrerade elektroniksystem; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Massive MIMO; Large Intelligent Surface LIS ; distributed processing; algorithm-architecture codesign; equalization; inter-connection data-rate;

   Sammanfattning : As 5G is entering maturity, the research interest has shifted towards 6G, and specially the new use cases that the future telecommunication infrastructure needs to support. These new use cases encompass much higher requirements, specifically: higher communication data-rates, larger number of users, higher accuracy in localization, possibility to wirelessly charge devices, among others. LÄS MER