Sökning: "antiretroviral"
Visar resultat 1 - 5 av 152 avhandlingar innehållade ordet antiretroviral.
1. Low-level HIV viremia during antiretroviral therapy
Sammanfattning : In most cases, antiretroviral therapy (ART) results in undetectable plasma HIV viral load (VL). Still, up to 25% of ART recipients may have detectable low-level viremia (LLV) of different amplitude and persistence. This thesis explores the impact of LLV during ART on virologic and clinical outcomes. LÄS MER
2. Antiretroviral treatment of HIV-1 in the central nervous system
Sammanfattning : HIV-1 invades the central nervous system (CNS) early in the infectious course. It establishes a chronic progressive infection, and triggers an intrathecal immune response. If left untreated, a majority of patients will develop neurological complications, caused by opportunistic pathogens or HIV-1 itself. LÄS MER
3. Pharmacometric Models to Improve Treatment of Tuberculosis
Sammanfattning : Tuberculosis (TB) is the world’s most deadly infectious disease and causes enormous public health problems. The comorbidity with HIV and the rise of multidrug-resistant TB strains impede successful therapy through drug-drug interactions and the lack of efficient second-line treatments. LÄS MER
4. Antiretroviral treatment of HIV-1 in Sweden with focus on virological aspects
Sammanfattning : From a clinical standpoint, there are many factors to consider when optimizing the care for people living with HIV (PLWH). With help from clinical guidelines, most obstacles can be addressed. Expanded knowledge is however in constant demand, from local conditions to universal processes. LÄS MER
5. Adherence and Readiness to Antiretroviral Treatment
Sammanfattning : Antiretroviral therapy places extraordinarily high demands on adherence, since non-adherence affects both individuals and society due to the spread of resistant viral strains. The aims of the thesis were to investigate the prevalence of adherence in Swedish HIV-infected patients, changes in adherence over time, and factors associated with adherence, including patients’ readiness to adhere. LÄS MER