Sökning: "carbohydrates."

Visar resultat 21 - 25 av 311 avhandlingar innehållade ordet carbohydrates..

  1. 21. Structure Elucidations of Bacterial Polysaccharides using NMR Spectroscopy and Bioinformatics

    Författare :Jonas Ståhle; Göran Widmalm; Evgeny Vinogradov; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Carbohydrates; Bioinformatics; NMR Spectroscopy; Lipopolysaccharide; Glycosyltransferase; Computer-Assisted Structure Elucidation; O-antigen; Biosynthesis; Organic Chemistry; organisk kemi;

    Sammanfattning : Carbohydrates are ubiquitous components in nature involved in a range of tasks. They cover every cell and contribute both structural stability as well as identity. Lipopolysaccharides are the outermost exposed part of the bacterial cell wall and the primary target for host-pathogen recognition. LÄS MER

  3. 22. Iridium Catalyzed Carbon- Heteroatom Bond Forming Reactions via Hydrogen Transfer : Method Development and Mechanistic Elucidations

    Författare :Aitor Bermejo López; Belén Martín‐Matute; Eduardo Peris; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Catalysis; N-Heterocyclic carbene; N-Alkylation; Hydrogen transfer; Amino acids; Carbohydrates; Amines; Organic Chemistry; organisk kemi;

    Sammanfattning : The present thesis describes the applicability of two different iridium(III) complexes for C-O and C-N bond forming reactions. The different projects described in this work are united by the use of an iridium catalyst bearing a functionalized N-heterocyclic carbene ligand. LÄS MER

  4. 23. NMR spectroscopy in structural and conformational analysis of bacterial polysaccharides

    Författare :Carolina Fontana; Göran Widmalm; Sven Müller-Loennies; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Nuclear Magnetic Resonance; carbohydrates; O-antigen polysaccharide; organisk kemi; Organic Chemistry;

    Sammanfattning : Carbohydrates constitute one of the three major classes of biomolecules found in all living cells and, unlike nucleic acids and proteins, their polymeric structures are not based on a template. The structural diversity of these molecules confers them an enormous capacity to encode information in biological systems, acting as efficient mediators in the interaction of the cell with the environment. LÄS MER

  5. 24. HIV-1 envelope protein gp120. Glycovirology of the V3 loop

    Författare :Britt Losman; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; AIDS; HIV-1; Carbohydrates; V3-region; V1-region; Coreceptors;

    Sammanfattning : The human immunodeficiency virus type 1 (HIV-1) infection usually is lethal as a consequence of the acquired immunodeficiency syndrome (AIDS). HIV-1 is an enveloped virus and the trimeric envelope glycoprotein complex, gp120/gp41, is responsible for binding of the virus both to the primary cellular receptor CD4 and the coreceptors, CXCR4 and CCR5. LÄS MER

  7. 25. Diabetes mellitus and risk of prostate cancer - A focus on shared risk factors and survivor bias

    Författare :Isabel Drake; Nutritionsepidemiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; carbohydrates; cohort; competing risk; diabetes mellitus; diet; epidemiology; fiber; gene; gene-environment; lifestyle; prostate cancer; survivor bias; transcription factor 7-like 2; whole-grain; alkylresorcinol metabolites;

    Sammanfattning : Prostate cancer (PCa) is a heterogenous disease including very aggressive lethal tumors to incidentally discovered clinically insignificant tumors. Age, ethnicity, and family history are the only established risk factors. LÄS MER