Sökning: "Belén Martín‐Matute"

Hittade 4 avhandlingar innehållade orden Belén Martín‐Matute.

  1. 1. Iridium Catalyzed Carbon- Heteroatom Bond Forming Reactions via Hydrogen Transfer : Method Development and Mechanistic Elucidations

    Författare :Aitor Bermejo López; Belén Martín‐Matute; Eduardo Peris; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Catalysis; N-Heterocyclic carbene; N-Alkylation; Hydrogen transfer; Amino acids; Carbohydrates; Amines; Organic Chemistry; organisk kemi;

    Sammanfattning : The present thesis describes the applicability of two different iridium(III) complexes for C-O and C-N bond forming reactions. The different projects described in this work are united by the use of an iridium catalyst bearing a functionalized N-heterocyclic carbene ligand. LÄS MER

  2. 2. Enols and Allylic Alcohols as Building Blocks in Synthetic Organic Chemistry : Experimental and Theoretical Studies

    Författare :Alba Carretero Cerdán; Belén Martín‐Matute; Shu-Li You; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Base catalysis; Ion-pair; Isomerization; MOFs; Hypervalent Iodine III ; DFT; Organic Chemistry; organisk kemi;

    Sammanfattning : The present thesis describes computational and experimental studies used to drive the reactivity of allylic and enol substrates towards new transformations. These synthetic methods give access to a number of organic molecules that may serve as important moieties in synthetic organic chemistry. LÄS MER

  3. 3. Selective Transformations of Allylic Compounds and Enol Derivatives : Synthesis of Fluorinated and Nitrogenated Scaffolds

    Författare :Víctor García-Vázquez; Belén Martín‐Matute; Mario Waser; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Fluorinated compounds; Base catalysis; Ion-Pair; Isomerization; Pd catalysis; Method development; Hypervalent iodine III ; Organic Chemistry; organisk kemi;

    Sammanfattning : In this thesis, new synthetic methods to give access to molecules having fluorinated scaffolds and other polar functional groups have been developed. The methods give access to highly valuable organic compounds that may serve as building blocks in the synthesis of functionalized drug candidates. LÄS MER

  4. 4. Iridium-Catalyzed C−H Activation Methods for Late-Stage Functionalization of Pharmaceuticals

    Författare :Erik Weis; Belén Martín‐Matute; Jin-Quan Yu; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; amination; catalysis; C-H activation; C-H functionalization; high-throughput experimentation; iodination; iridium; isotope labelling; late-stage functionalization; methylation; Organic Chemistry; organisk kemi;

    Sammanfattning : C-H activations have over the recent decades risen from a mere curiosity to a viable synthetic strategy. However, challenges in terms of accessible transformations, selectivity and functional group tolerance limit the widespread applicability of this approach. LÄS MER