Sökning: "bone remodeling"

Visar resultat 11 - 15 av 69 avhandlingar innehållade orden bone remodeling.

1. 11. BMP implants in bone formation. Studies in rabbits and rats

   Författare :Charlotte Jeppsson; Malmö Handkirurgi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ortopedi; traumatologi; graft resorption.; Kirurgi; Surgery; orthopaedics; traumatology; bone formation; bone graft; hydroxyapatite; collagen; bisphosphonate; rat; rabbit; titanium chamber; BMP; TGF-ß;

   Sammanfattning : Bone morphogenic proteins, BMPs, are a group endogenous proteins that are highly conserved through evolution. The amino acid sequences of about 15 different BMPs are now known and recombinant human BMPs are commercially available. Implantation of an individual BMP protein is sufficient to induce bone formation even at a subcutaneous site. LÄS MER

3. 12. On a biomechanical approach to analysis of stability and load bearing capacity of oral implants

   Författare :Anders Halldin; Malmö högskola; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; animal model; bone resorption; implant stability; cortical bone; viscoelastic-viscoplastic; creep remodeling; constitutive model;

   Sammanfattning : IntroductionWhen an implant is placed in the bone the body responds to thetrauma by encapsulating the implant and its survival depends onthe ability for hard tissue encapsulation. The stability of the implantduring the healing phase is essential to achieve a good result[1]. Biological, physiological and mechanical phenomena affectimplant stability. LÄS MER

4. 13. The morselized and impacted bone graft. Animal experiments on proteins, impaction and load

   Författare :Magnus Tägil; Lund Ortopedi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; traumatology; orthopaedics; Surgery; load; growth factors; graft healing; remodeling; allograft; Impaction grafting; morselized graft; Kirurgi; ortopedi; traumatologi; Immunology; serology; transplantation; Immunologi; serologi;

   Sammanfattning : This thesis focuses on the healing and remodeling of the morselized and impacted bone allograft, commonly used in revision of loosened hip prostheses with osteolysis. The influence on remodeling by the impaction procedure per se was analyzed, as well as the effects of endogenous bone graft proteins, and an exogenously applied growth factor (OP-1). LÄS MER

5. 14. The role of estrogen receptor alpha in the regulation of bone and growth plate cartilage

   Författare :Anna E Börjesson; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; estrogen receptor α; bone; growth plate; estrogen;

   Sammanfattning : Estrogens are important endocrine regulators of skeletal growth and maintenance in both females and males. Studies have demonstrated that the estrogen receptor (ER)-α is the main mediator of these estrogenic effects in bone. Therefore, estrogen signaling via ERα is a target both for affecting longitudinal bone growth and for bone remodeling. LÄS MER

7. 15. On the Role of Osteoprotegerin/RANK/RANKL System in the Interaction between Prostate Cancer and Bone

   Författare :Hendrik Penno; Östen Ljunggren; Olof Nilsson; Andreas Kindmark; Pernilla Lundberg; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; metastases; bone; prostate cancer; osteoprotegerin; RANKL; osteoporosis; genetics; polymorphisms; Orthopaedics; Ortopedi;

   Sammanfattning : Metastases to bone are observed in around 80% of prostate cancer patients and represent the most critical complication of advanced prostate cancer. Unlike other solid tumors that are associated with osteolytic bone metastases, prostate cancer bone metastases stimulate osteoblastic activity with sclerosis in the bone lesions as a consequence. LÄS MER