Sökning: "Hendrik Penno"

Hittade 1 avhandling innehållade orden Hendrik Penno.

1. 1. On the Role of Osteoprotegerin/RANK/RANKL System in the Interaction between Prostate Cancer and Bone

   Författare :Hendrik Penno; Östen Ljunggren; Olof Nilsson; Andreas Kindmark; Pernilla Lundberg; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; metastases; bone; prostate cancer; osteoprotegerin; RANKL; osteoporosis; genetics; polymorphisms; Orthopaedics; Ortopedi;

   Sammanfattning : Metastases to bone are observed in around 80% of prostate cancer patients and represent the most critical complication of advanced prostate cancer. Unlike other solid tumors that are associated with osteolytic bone metastases, prostate cancer bone metastases stimulate osteoblastic activity with sclerosis in the bone lesions as a consequence. LÄS MER