Sökning: "hydroxyapatite"

Visar resultat 1 - 5 av 109 avhandlingar innehållade ordet hydroxyapatite.

1. 1. Fixation of Spinal Implants : Clinical and Experimental Studies on the Effects of Hydroxyapatite Coating

   Författare :Bengt Sandén; Acke Ohlin; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; Hydroxyapatite; pedicle screw; histomorphometry; fixation; radiolucent zones; screw loosening; Kirurgi; Surgery; Kirurgi; Orthopaedics; ortopedi;

   Sammanfattning : Loosening of implants is a frequent complication in orthopaedic surgery. The aim of this thesis was to evaluate hydroxyapatite coating of pedicle screws with mechanical and histological methods and to correlate the results with the radiological findings.Hydroxyapatite (HA) coating of pedicle screws was investigated in experimental studies in sheep. LÄS MER

3. 2. Hydroxyapatite – A trojan horse in the delivery of apatite-binding cytostatics in bone cancer

   Författare :Yang Liu; Lund Ortopedi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biomaterials; Hydroxyapatite; osteosarcoma; Doxorubicin; Local delivery;

   Sammanfattning : Osteosarcoma is a malignant cancer of the bone mainly affecting adolescents. Despite progress, the clinical management of osteosarcoma is still challenging. With the current chemotherapy protocol being used for more than 30 years, the number of poor responders is increasing. LÄS MER

4. 3. Spark Plasma Sintering Enhancing Grain Sliding, Deformation and Grain Size Control : Studies of the Systems Ti, Ti/TiB2, Na0.5 K0.5 NbO3, and Hydroxyapatite

   Författare :Mirva Eriksson; Zhijian Shen; Takashi Goto; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Spark plasma sintering; plastic deformation; grain growth; titanium; TiB2; hydroxyapatite; Na0.5K0.5NbO3; ferroelectric; transparent; Materials chemistry; Materialkemi; Materials Chemistry; materialkemi;

   Sammanfattning : The unique features of the Spark plasma sintering (SPS) were used to investigate the sintering and deformation behaviour of titanium and titanium–titanium diboride composites, and to control the sintering and grain growth of ferroelectric Na0.5K0.5NbO3 (NKN) and of hydroxyapatite (HAp). LÄS MER

5. 4. On Bone Regeneration in Porous Bioceramics - Studies in humans and rabbits using free form fabricated scaffolds

   Författare :Johan Malmström; Göteborgs universitet; []
   Nyckelord :bone regeneration; hydroxyapatite; zirconia; macroporosity; microporosity; free form fabrication; focused ion beam; scanning electron microscopy; transmission electron microscopy; rabbit; human;

   Sammanfattning : The objective of the present thesis was to evaluate the effect of material chemistry and macroand micro-porosity on bone regeneration in association with synthetic, porous ceramic materials. Ceramic scaffolds were designed and manufactured for experimental and human studies using free form fabrication (FFF), a technique which produces the object layer by layer using data from CAD files. LÄS MER

7. 5. Bone Healing after implantation of bone substitute materials. Experimental studies in estrogen deficiency

   Författare :Sven Öberg; Jan Rosenquist; Ulf Lekholm; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; Bone grafts; hydroxyapatite; estrogen deficiency; demineralised bone; bone formation; AAA bone; bone defect; titanium implants; resonance frequency analysis.; Kirurgi; Surgery; Kirurgi; kirurgi; Surgery;

   Sammanfattning : Bone formation and bone healing were studied in the mandible, tibia and skull bones in adult, healthy and estrogen deficient rabbits implanted with different bone substitutes.In the first study an evaluation of the differences in bone regeneration in and around solid (Alveograf *) and porous hydroxyapatite (Interpore 200*) was undertaken. LÄS MER