Sökning: "graft resorption."

Visar resultat 1 - 5 av 20 avhandlingar innehållade orden graft resorption..

  1. 1. BMP implants in bone formation. Studies in rabbits and rats

    Författare :Charlotte Jeppsson; Malmö Handkirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ortopedi; traumatologi; graft resorption.; Kirurgi; Surgery; orthopaedics; traumatology; bone formation; bone graft; hydroxyapatite; collagen; bisphosphonate; rat; rabbit; titanium chamber; BMP; TGF-ß;

    Sammanfattning : Bone morphogenic proteins, BMPs, are a group endogenous proteins that are highly conserved through evolution. The amino acid sequences of about 15 different BMPs are now known and recombinant human BMPs are commercially available. Implantation of an individual BMP protein is sufficient to induce bone formation even at a subcutaneous site. LÄS MER

  2. 2. The morselized and impacted bone graft. Animal experiments on proteins, impaction and load

    Författare :Magnus Tägil; Lund Ortopedi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; traumatology; orthopaedics; Surgery; load; growth factors; graft healing; remodeling; allograft; Impaction grafting; morselized graft; Kirurgi; ortopedi; traumatologi; Immunology; serology; transplantation; Immunologi; serologi;

    Sammanfattning : This thesis focuses on the healing and remodeling of the morselized and impacted bone allograft, commonly used in revision of loosened hip prostheses with osteolysis. The influence on remodeling by the impaction procedure per se was analyzed, as well as the effects of endogenous bone graft proteins, and an exogenously applied growth factor (OP-1). LÄS MER

  3. 3. On tissue reactions to and resorption of bone substitutes

    Författare :Arne Mordenfeld; Malmö högskola; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; bone graft; bone substitutes; sinus floor augmentation; lateral ridge augmentation;

    Sammanfattning : Background: The increasing need for bone grafting procedures inimplant dentistry and the introduction of a variety of bone substitutesrequire a deeper understanding of the biological response and shortandlong-term behaviour of these materials to choose the adequategraft and surgical procedure for the intended clinical application.Aims: The overall aim was to clinically and histologically studythe short- and long-term tissue reactions to and resorption of bonesubstitutes after bone augmentation. LÄS MER

  4. 4. Biological interface of bone graft substitute materials : experimental studies on interactions between biomaterials and bone cells

    Författare :Zivko Mladenovic; Maria Ransjö; Joost D de Brujin; Umeå universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Bone graft substitute materials are becoming more common as alternative therapy strategies when bone defects in patients need to be treated. The interaction between bone cells and biomaterials occur at the surface of the materials. A great deal is known about the importance of surface topography and physic-chemical properties of biomaterials. LÄS MER

  5. 5. Bisphosphonates for orthopedic applications. Studies in rat models

    Författare :Jörgen Åstrand; Lund Ortopedi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; traumatology; Kirurgi; ortopedi; traumatologi; orthopaedics; Surgery; topical treatment; osteonecrosis; bone graft resorption; prosthetic loosening; Bisphosphonates; osteoclasts;

    Sammanfattning : Prosthetic loosening, bone graft resorption and osteonecrosis are examples of problems in orthopedic surgery caused by or augmented by bone resorption. Bone resorption is caused by osteoclasts. Osteoclasts can be inactivated with biphosphonates, a drug in clinical use against osteoporosis and osteolytic tumors. LÄS MER