Sökning: "Selection Genetics"

Visar resultat 11 - 15 av 243 avhandlingar innehållade orden Selection Genetics.

  1. 11. Domestication Effects on the Stress Response in Chickens : Genetics, Physiology, and Behaviour

    Författare :Amir Fallahshahroudi; Per Jensen; Frank Albert; Linköpings universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; Animal domestication; stress response; gene expression; QTL; eQTL;

    Sammanfattning : Animal domestication, the process where animals become adapted to living in proximity to humans, is associated with the alteration of multiple traits, including decreased fearfulness and stress response. With an estimated population of 50 billion, the domesticated chicken is the most populous avian species in the world. LÄS MER

  3. 12. Evolution of MHC Genes and MHC Gene Expression

    Författare :Karin Berggren Bremdal; Hans Ellegren; Jennifer Seddon; Philip Hedrick; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; major histocompatibilty complex; dog leukocyte antigen; balancing selection; linkage disequilibrium; promoter; diabetes mellitus; Canis familiaris; Canis lupus; Erinaceus europaeus; Erinaceus concolor; Genetics; Genetik; Biology with specialization in Evolutionary Genetics; Biologi med inriktning mot evolutionär genetik;

    Sammanfattning : Polymorphism in coding regions and regions controlling gene expression is the major determinant of adaptive differences in natural populations. Genes of the major histocompatibility complex (MHC) possess a high level of genetic variation, which is maintained by selection over long coalescence times. LÄS MER

  4. 13. Immunoglobulin Gene Analysis in Different B cell Lymphomas : With Focus on Cellular Origin and Antigen Selection

    Författare :Mia Thorsélius; Richard Rosenquist Brandell; Christer Sundström; Anders Rosén; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; B cell lymphoma; Immunoglobulin; V gene; somatic hypermutation; antigen selection; quantitative PCR; Genetik; Clinical genetics; Klinisk genetik;

    Sammanfattning : B cell lymphoma (BCL) comprises a biologically and clinically heterogeneous group of tumors deriving from different stages of B cell development. The immunoglobulin (Ig) variable heavy chain (VH) gene rearrangement is unique for each BCL and can be used to reveal cellular origin, to study signs of antigen selection and to quantify tumor cell load. LÄS MER

  5. 14. Population genomic analyses of regulatory variation and selection in Brassicaceae species

    Författare :Robert Horvath; Tanja Slotte; Peter Hambäck; Douglas G. Scofield; Matthew Webster; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Capsella grandiflora; Arabidopsis thaliana; Arabidopsis lyrata; natural selection; gene expression variation; DNA and gene body methylation; transposable elements; DNA accessibility; gene expression noise; epigenetic silencing; linked selection; ekologi och evolution; Ecology and Evolution;

    Sammanfattning : The impact of selection on regulatory variation and the contribution of regulatory changes to phenotypic variation has long been debated in evolutionary genetics. Because cis-regulatory elements such as promoters and enhancers can be difficult to identify, it has been more challenging to quantify the impact of selection on variation in cis-regulatory regions than in protein-coding regions. LÄS MER

  7. 15. Immunity & the butterfly : A functional genomic study of natural variation in immunity

    Författare :Naomi L.P. Keehnen; Christopher W. Wheat; Brian Lazzaro; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; eco-immunology; functional genomics; transcriptomics; innate immunity; selection dynamics; melanization; phagocytosis; population genetics; Pieris napi; populationsgenetik; Population Genetics;

    Sammanfattning : Butterflies are ubiquitous and abundant, occurring in a wide variety of environments that contain diverse microbial communities with varied pathogenic pressures. These pathogens and parasites present a constant threat to organisms, and have led to the evolution of complex and intricate immune responses. LÄS MER