Sökning: "promoter"

Visar resultat 1 - 5 av 770 avhandlingar innehållade ordet promoter.

  1. 1. Promoter Engineering for Cyanobacteria : An Essential Step

    Författare :Hsin-Ho Huang; Peter Lindblad; James Golden; Uppsala universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; synthetic biology; cyanobacteria; promoter; engineering; TetR; DNA breathing dynamics; transcription; regulation;

    Sammanfattning : Synthetic biology views a complex biological system as an ensemble in the hierarchy of parts, devices, systems, and networks. The practice of using engineering rules such as decoupling and standardization to understand, predict, and re-build novel biological functions from model-driven designed genetic circuits is emphasized. LÄS MER

  2. 2. TARP Promoter-Based Prostate Cancer Gene Therapy : From Development to Application

    Författare :Wing-Shing Cheng; Magnus Essand; Thomas H. Tötterman; Cecilia Lundberg; Uppsala universitet; []
    Nyckelord :ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Genetic engineering; TARP; PPT; TSTA; promoter; gene regulation; prostate specificity; hormone- independent; adenovirus; prostate cancer; gene therapy; conditionally replicating adenovirus; Genteknik; Genetic engineering including functional genomics; Genteknik inkl. funktionsgenomik;

    Sammanfattning : Prostate cancer is one leading cause of cancer-related death among men in Western countries. The standard therapies for localized prostate cancer include radical prostatectomy and radiation therapy. Such measures are relatively effective in the short term, but many patients ultimately relapse. LÄS MER

  3. 3. Development of a Novel Promoter System for Thioglycoside Activation; and its application in the synthesis of a GD3 bis-lactam

    Författare :Andréas Meijer; Centrum för analys och syntes; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; GD3; Organic chemistry; bis-lactam; ganglioside; thioglycoside; promoter; iodine monobromide; glycosylation; iodine monochloride; Organisk kemi;

    Sammanfattning : A novel promoter system IX/AgOTf (X=Cl or Br) for thioglycoside activation has been developed (paper I-II). The promoter system has been evaluated in the synthesis of two GD3 bis-lactam fragments (paper III)... LÄS MER

  4. 4. Functional Studies on the PDGFR α gene promoter and effects of autocrine PDGF-A stimulation in vivo

    Författare :Xiao-Qun Zhang; Hubert Schorle; Uppsala universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; Autorcrine PDGF; promoter; PDGFRA; transgenic mice; Genetik; Clinical genetics; Klinisk genetik; Pathology; patologi;

    Sammanfattning : Platelet-derived growth factor receptor α (PDGFRα) plays an important role during embryogenesis. After implantation, the patterns of expression of Pdgfrα and its ligand Pdgf-A undergo an "autocrine-paracrine transition", in that Pdgf-A becomes expressed in the ectoderm and epithelia, while Pdgfrα is expressed in the adjacent mesenchymal tissue. LÄS MER

  5. 5. Studies of immunoglobulin light chains in rainbow trout (Oncorhynchus mykiss): new insight into the evolution of immunoglobulin genes

    Författare :Sirje Timmusk; Greg Warr; Uppsala universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Cell and molecular biology; Immunoglobulin genes; gene organization; evolution; comparative immunology; promoter; rainbow trout Oncorhynchus mykiss ; Cell- och molekylärbiologi; Cell and molecular biology; Cell- och molekylärbiologi; molekylär immunologi; Molecular Immunology;

    Sammanfattning : In this thesis, the structure and the expression of immunoglobulin (Ig) light chain genes were studied in rainbow trout and including an evolutionary perspective. A novel Ig light chain locus (IgL2) was identified and characterized. LÄS MER