Sökning: "Schizophrenia"

Visar resultat 6 - 10 av 263 avhandlingar innehållade ordet Schizophrenia.

  1. 6. Prognostic Factors in First-Episode Schizophrenia : Five-year Outcome of Symptoms, Function and Obesity

    Författare :Robert Bodén; Johan Sundström; Leif Lindström; Lena Flyckt; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; First-episode; psychosis; schizophrenia; community mental health services; remission; functional outcome; biochemistry; obesity; weight-gain; prediction; autonomic balance; electrocardiography; Psychiatry; Psykiatri; Psychiatry; Psykiatri;

    Sammanfattning : Our knowledge of prognostic factors and optimal treatment organisation in schizophrenia is incomplete. The disparity of outcome measures used has been a major obstacle for research. Increasing evidence has shown that schizophrenia is associated with increased cardiovascular mortality, development of obesity and autonomic nervous system imbalance. LÄS MER

  3. 7. Finding improved drug strategies for schizophrenia : Preclinical studies on lumateperone and sodium nitroprusside

    Författare :Joep Titulaer; Åsa Konradsson-Geuken; Anne-Lie Svensson; Erika Roman; Kent Jardemark; Joshua Beckmann; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; schizophrenia; lumateperone; sodium nitroprusside; antipsychotic drugs; Farmaceutisk vetenskap; Pharmaceutical Science; Pharmacology; Farmakologi; Psychiatry; Psykiatri;

    Sammanfattning : Schizophrenia is a severe psychiatric disorder affecting approximately 20 million people worldwide. The disease consists of positive symptoms e.g. hallucinations, negative symptoms such as anhedonia, and cognitive deficits, e. LÄS MER

  4. 8. Diagnostic Evaluation of Schizophrenia for Genetic Studies

    Författare :Birgit Ekholm; Rolf Adolfsson; Erik Jönsson; Göran Sedvall; Leif Lindström; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Psychiatry; Schizophrenia; Diagnostic evaluation; Molecular genetic studies; Linkage; Association; Psykiatri; Psychiatry; Psykiatri; psykiatri; Psychiatry;

    Sammanfattning : Schizophrenia is one of the most severe mental disorders. Heredity is accepted as a major causative factor. To find molecular mechanisms behind schizophrenia, patient materials with reliable and valid diagnoses must be identified. LÄS MER

  5. 9. Early trauma/dysmorphogenesis and adult neurodysfunction in schizophrenia

    Författare :Baher Ismail; Avdelningen för arbets- och miljömedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Psychiatry; clinical psychology; klinisk psykologi; neurodevelopmental model; psychosomatics; Psykiatri; tardive dyskinesia; neurological abnormality; neurocognitive dysfunction; dermatoglyphics; head circumference; minor physical anomalies; Schizophrenia; obstetric complications; psykosomatik;

    Sammanfattning : To measure the importance of early neurodevelopmental disturbance for schizophrenia, early trauma and dysmorphogenesis (i.e. obstetric complications (OCs), minor physical anomalies (MPAs), head circumference (HC) and dermatoglyphic characteristics) were studied in relationship to adult neurodysfunction (i.e. LÄS MER

  7. 10. Cognitive function studied in animal models of schizophrenia

    Författare :Erik Pålsson; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; phencyclidine; nitric oxide; prepulse inhibition; latent; nitric oxide; prepulse inhibition; latent inhibition; habituation; NMDA receptor; rat; mouse; cognition; schizophrenia;

    Sammanfattning : Cognitive dysfunction is considered a core deficit of schizophrenia, which currently lacks effective pharmacological treatment. In order to identify novel and more effective drug treatments, translational experimental animal models of cognitive dysfunction are required. Schizophrenia-like symptoms can be induced in humans by phencyclidine (PCP). LÄS MER