Sökning: "Maturation"
Visar resultat 36 - 40 av 635 avhandlingar innehållade ordet Maturation.
36. Thermal Modelling of the Caledonian Basin, Scandinavia and a Northern North Sea Profile
Sammanfattning : The reason for the registered high paleotemperatures of the Scandinavian Alum Shale was investigated by heat flow modelling constrained by vitrinite-like reflectance. The behaviour of the lithosphere under a load was modelled and the paleotemperatures were explained by burial of the Alum Shale in a foreland basin, developing during the Caledonian orogeny. LÄS MER
37. G protein-coupled receptor regulation: The role of protein interactions and receptor trafficking
Sammanfattning : The superfamily of G protein-coupled receptors (GPCR) is the largest gene family in the human genome. GPCR-mediated signaling operates in every human cell, and about 50% of existing clinically useful drugs act through GPCR. LÄS MER
38. Selection and design in antibody phage display
Sammanfattning : The immune system is an important part of the physiology of higher organisms. In the immune system antibodies play a key role in neutralizing and clearing potentially lethal threats from the environment. The importance of antibodies in the immune system has made them come to the attention as a tool in chemistry and medicine. LÄS MER
39. Mechanisms by which variants in the TCF7L2 gene increase the risk of developing Type 2 diabetes
Sammanfattning : Type 2 diabetes mellitus (T2DM) is a heterogeneous disease with a multifactorial aetiology comprising of genetic and environmental factors. The common variant most highly associated with T2DM known to date is a SNP rs7903146 in the TCF7L2 gene. However, the role TCF7L2 plays in the development of T2DM was unclear. LÄS MER
40. Oligodendroglial (dys)function in alpha-synucleinopathies
Sammanfattning : The complexity of a-synucleinopathies, which include multiple system atrophy (MSA) and Parkinson’s disease (PD), is not entirely understood. It is known that pathological accumulation of a-synuclein (a-syn) into proteinaceous aggregates is a cellular hallmark of these diseases. LÄS MER