Sökning: "B1R"

Hittade 2 avhandlingar innehållade ordet B1R.

1. 1. G protein-coupled receptor regulation: The role of protein interactions and receptor trafficking

   Författare :Caroline Sandén; Drug Target Discovery; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; receptor trafficking; B1 receptor; receptor oligomerization; estrogen; GPER1; G protein-coupled estrogen receptor 1; EP24.15; BK; bradykinin; B1R; B2R; B2 receptor; GPCR; receptor maturation;

   Sammanfattning : The superfamily of G protein-coupled receptors (GPCR) is the largest gene family in the human genome. GPCR-mediated signaling operates in every human cell, and about 50% of existing clinically useful drugs act through GPCR. LÄS MER

3. 2. The Role of Membrane Trafficking in G Protein-Coupled Receptor Regulation

   Författare :Johan Enquist; Drug Target Discovery; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicin människa och djur ; Medicine human and vertebrates ; downregulation; recycling; resensitization; desensitization; GPCR; membrane trafficking;

   Sammanfattning : Movements of a receptor in the plasma membrane and within the cell influence receptor function and physiology. I have investigated the role of such movements, generally known as membrane trafficking, in G protein-coupled receptor regulation. LÄS MER