Sökning: "Invasion biology"

Visar resultat 6 - 10 av 77 avhandlingar innehållade orden Invasion biology.

  1. 6. Proliferation, Invasion and p16 Localisation in Malignancies

    Författare :Kristina Nilsson; Malmö Patologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; onkologi; Cytologi; cancerology; Cytology; oncology; skin tumours; invasion; p16; cancer; patologisk anatomi; Patologi allmän ; pathological anatomy; proliferation; General pathology;

    Sammanfattning : Uncontrolled proliferation and invasion are two characteristics in tumour development and progression. Previous studies have shown that invading tumour cells in colorectal cancer have low proliferation in parallel to upregulation of the tumour suppressor p16. LÄS MER

  3. 7. The role of Smad7 and TRAF6 in Prostate Cancer Cell Invasion, Migration and Survival

    Författare :Maria Ekman; Marene Landström; Carl-Henrik Heldin; Jonas Fuxe; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TGF-beta; cell migration; invasion; apoptosis; Smad7; APC; ATM; TRAF6; p53; PC3U; Medical Cell Biology; Medicinsk cellbiologi;

    Sammanfattning : Transforming growth factor (TGF) β is a tumor suppressor during early tumor development, by inhibiting proliferation and inducing apoptosis. At later stages of cancer, it becomes a tumor promoter, and promotes tumor cell migration and invasion. TGFβ signals via its type II and type I receptors to several downstream signaling pathways. LÄS MER

  4. 8. Nanoscopic adventures : unraveling macromolecular complexes in infectious diseases via integrative structural biology

    Författare :Kai Patric Ehrenbolger; Ronnie Berntsson; Felipe Cava; Jonas Barandun; David Drew; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Infectious diseases; E. faecalis; Microsporidia; Ribosome; Proteasome; Polar Tube; Structural Biology; Single particle Cryo-Electron Microscopy;

    Sammanfattning : This thesis focuses on understanding the underlying molecular mechanisms of infectious diseases, which claim nearly 9 million lives annually. The research centers on critical analysis of pathogen mechanisms and drug resistance. I have mainly focused on two clades of pathogens: Enterococcus faecalis and microsporidia. E. LÄS MER

  5. 9. RsbX and stress response in Listeria monocytogenes

    Författare :Ana Henriques de Oliveira; Jörgen Johansson; Cormac Gahan; Umeå universitet; []
    Nyckelord :LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Listeria monocytogenes; SigB; stressosome; RsbX; phosphorylation; growth; competitiveness; motility; energetic cost; homeostasis; stress response; virulence; invasion; molekylärbiologi; Molecular Biology; mikrobiologi; Microbiology;

    Sammanfattning : Listeria monocytogenes is a ubiquitous foodborne Gram-positive bacterium. Despite being mainly a soil bacterium, it can reach the food processing environment and contaminate food destined for human consumption, causing outbreaks. LÄS MER

  7. 10. Canonical and non-canonical functions of METTL3 in breast cancer

    Författare :Cyrinne Achour; Francesca Aguilo; Jonathan D. Gilthorpe; Jean-Yves Roignant; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; RNA modification; METTL3; m6A; alternative splicing; exocyst; breast cancer;

    Sammanfattning : Gene expression is spatially and temporally regulated at multiple levels. N6-methyladenosine (m6A) is the most prevalent internal modification in messenger RNA (mRNA) and long noncoding RNA (lncRNAs). LÄS MER