Sökning: "Host proteins"

Visar resultat 16 - 20 av 572 avhandlingar innehållade orden Host proteins.

1. 16. Host-pathogen interactions during tick-borne flavivirus infection : pathogenesis, tropism and tools

   Författare :Ebba Rosendal; Anna K. Överby Wernstedt; Emma Nilsson; Jonathan D. Gilthorpe; Sonja M. Best; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Tick-borne encephalitis virus; Langat virus; pathogenesis; type I interferons; central nervous system; neuroinflammation; structural proteins; Infectious Diseases; infektionssjukdomar; mikrobiologi; Microbiology;

   Sammanfattning : Tick-borne encephalitis virus (TBEV) is a neurotropic member of the genus Flavivirus. It may transmit to humans through the bite of an infected tick or consumption of unpasteurized dairyproducts, and causes tick-borne encephalitis (TBE). TBE constitutes a significant health burden in Eurasia, with more than 10,000 cases reported every year. LÄS MER

3. 17. Staphylococcal cell wall associated proteins : characteristics and host interactions

   Författare :Anna Bjertsjö Rennermalm; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Staphylococcus; aureus; epidermidis; cell wall; surface; protein; fibronectinbinding protein; fibrinogen binding protein; internalisation; immunisation; endocarditis; opsonisation;

   Sammanfattning : Staphylococcus aureus and Staphylococcus epidermidis are members of the same family and share several features. S. aureus causes many diseases ranging from mild skin infections to deep tissue infections and septic shock. S. LÄS MER

4. 18. Determining the role of guanylate-binding proteins for host defense against Francisella tularensis

   Författare :Nasibeh Mohammadi; Anders Sjöstedt; Wolfgang P. Schröder; Anetta S. Härtlova; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Francisella tularensis; Guanylate-binding proteins; bone marrow-derived macrophages; IFN-γ activation; cytokine patterns; inflammasome pathways; co-infection; mouse co-culture model; Biochemistry; biokemi; immunologi; Immunology; mikrobiologi; Microbiology; molekylärbiologi; Molecular Biology; Infectious Diseases; infektionssjukdomar;

   Sammanfattning : Francisella tularensis is a highly virulent, intracellular bacterium and the causative agent of the human disease tularemia. This is a zoonotic, often vector-borne disease. Due to its intracellular nature, F. LÄS MER

5. 19. Proteomic profiling of bacterial host adaptation : Racing the Red Queen

   Författare :Ola Kilsgård; Institutionen för immunteknologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Proteomics; Mass Spectrometry; Systems biology; Biomarker; Host adaptation; Bacteria; Streptococcus pyogenes;

   Sammanfattning : Despite the discovery of antibiotics almost a century ago, infectious diseases continue to be a substantial cause of human mortality and morbidity worldwide, especially in developing countries. The adverse affects of infectious diseases are thought to increase over the coming years as the widespread misuse of antibiotic leads to the emergence of strains for which current therapies are ineffective. LÄS MER

7. 20. Infection biology of the plant pathogenic fungus Bipolaris sorokiniana

   Författare :Dace Apoga; Biologiska institutionen; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; microscopy; Hordeum vulgare; barley; virulence; prehelminthosporol; phytotoxins; proteins; adhesion; fimbriae; extracellular matrix; Helminthosporium sativum; Cochliobolus sativus; Plant pathogenic fungi; Bipolaris sorokiniana; two-dimensional gel electrophoresis; mass spectrometry; gas chromatography; Ecology; Ekologi;

   Sammanfattning : Bipolaris sorokiniana is a fungal pathogen causing severe disease mainly in wheat and barley worldwide. In this thesis two aspects of the infection process were investigated: the adhesion mechanism of the fungus and the role of the non-host specific phytotoxin prehelminthosporol (PHL) in the disease. Adhesion of B. LÄS MER