Sökning: "Langat virus"

Hittade 4 avhandlingar innehållade orden Langat virus.

1. 1. Host-pathogen interactions during tick-borne flavivirus infection : pathogenesis, tropism and tools

   Författare :Ebba Rosendal; Anna K. Överby Wernstedt; Emma Nilsson; Jonathan D. Gilthorpe; Sonja M. Best; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Tick-borne encephalitis virus; Langat virus; pathogenesis; type I interferons; central nervous system; neuroinflammation; structural proteins; Infectious Diseases; infektionssjukdomar; mikrobiologi; Microbiology;

   Sammanfattning : Tick-borne encephalitis virus (TBEV) is a neurotropic member of the genus Flavivirus. It may transmit to humans through the bite of an infected tick or consumption of unpasteurized dairyproducts, and causes tick-borne encephalitis (TBE). TBE constitutes a significant health burden in Eurasia, with more than 10,000 cases reported every year. LÄS MER

3. 2. Characterizing important flavivirus-host interactions : Replication, assembly, restriction factors and vaccine development

   Författare :Pham Tue Hung Tran; Magnus Johansson; Wessam Melik; Naveed Asghar; Sören Andersson; Laurent Chatel-Chaix; Örebro universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Flaviviruses; virus-host cell interaction; lunapark; ESCRT; ALIX; CHMP4A; ISG15; TRIMs; replicon virus-like particles; vaccine;

   Sammanfattning : The genus Flavivirus (family Flaviviridae) consists of important zoonotic viruses that cause morbidity and mortality worldwide. These viruses are enveloped and have a positive-sense single-stranded RNA genome encoding a polyprotein. LÄS MER

4. 3. Interplay between tick-borne encephalitis virus and the host innate immunity

   Författare :Chaitanya Kurhade; Anna Överby Wernstedt; Nelson Gekara; Helen Lazear; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Virology; Flavivirus; IPS-1; Interferon; Viperin; mikrobiologi; Microbiology;

   Sammanfattning : Flaviviruses are important emerging and re-emerging arthropod-borne pathogens that cause significant morbidity and mortality in humans. It consists of globally distributed human pathogens such as tick-borne encephalitis virus (TBEV), West Nile virus (WNV), Japanese encephalitis virus (JEV), yellow fever virus (YFV), dengue virus (DENV), and Zika virus (ZIKV). LÄS MER

5. 4. The role of the type I interferons and viperin during neurotropic flavivirus infection

   Författare :Richard Lindqvist; Anna Överby Wernstedt; Daniel Ruzek; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TBEV; Flavivirus; Interferon; Neurotropic; Viperin;

   Sammanfattning : Flaviviruses are globally distributed pathogens that cause millions of human infections annually. One of the most detrimental outcomes of flavivirus infection is encephalitis, which is caused by neurotropic flaviviruses such as West Nile virus (WNV), Japanese encephalitis virus (JEV), and Tick-borne encephalitis virus (TBEV). LÄS MER