Sökning: "fimbriae"

Visar resultat 1 - 5 av 49 avhandlingar innehållade ordet fimbriae.

  1. 1. Mechanisms of P fimbriae cell activation

    Författare :Maria Hedlund; immunologi och glykobiologi - MIG Avdelningen för mikrobiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; type 1 fimbriae; LPS; glycosphingolipids; ceramide; E. coli; P fimbriae; mucosa; cytokines; Microbiology; bacteriology; virology; mycology; Mikrobiologi; bakteriologi; virologi; mykologi;

    Sammanfattning : Microbial attachment to host cells plays a central role in the induction of inflammatory responses and the production of the disease. Uropathogenic Gram negative bacteria carry surface lectins that specifically recognize oligosaccharide receptor epitopes expressed on glycolipids or glycoproteins. LÄS MER

  3. 2. Escherichia coli Fimbriae, Bacterial Persistence and Host Response Induction in the Human Urinary Tract

    Författare :Göran Bergsten; immunologi och glykobiologi - MIG Avdelningen för mikrobiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mykologi; virologi; bakteriologi; Mikrobiologi; mycology; virology; bacteriology; Microbiology; IL-8; IL-6; neutrophils; GFP; mucosal host response; Type 1 fimbriae; P fimbriae; adherence; virulence factors; regulation; deliberate colonisation; Escherichia coli 83972; Urinary tract infection; asymptomatic bacteriuria;

    Sammanfattning : Urinary tract infections (UTI) are among the most common bacterial infections in humans. Symptomatic UTIs may be acute, recurrent or chronic but the most frequent form of UTI is asymptomatic bacteruria (ABU). In ABU, the mucosa remains inert, despite the presence of large bacterial numbers in urine. LÄS MER

  4. 3. Of spiders, bugs, and men : Structural and functional studies of proteins involved in assembly

    Författare :Wangshu Jiang; Stefan D Knight; Steve J. Matthews; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Protein assembly; sulfate transporter; crystallography; Proteus mirabilis; fimbriae; adhesin; urinary tract infection; biofilm; spider silk; asymmetric dimer; Bri2; BRICHOS; molecular chaperone; Alzheimer s disease; amyloid; Biology with specialization in Structural Biology; Biologi med inriktning mot strukturbiologi;

    Sammanfattning : Protein assembly enables complex machineries while being economical with genetic information. However, protein assembly also constitutes a potential threat to the host, and needs to be carefully regulated.Sulfate is a common source of sulfur for cysteine synthesis in bacteria. LÄS MER

  5. 4. Mucosal Vaccination Using Polyacryl Starch Microparticles as Adjuvant with Salmonella enteritidis as a Model Pathogen

    Författare :Lena Strindelius; Ingvar Sjöholm; Mary Jo Wick; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutics; mucosal vaccination; polyacryl starch microparticles; salmonella enteritidis; flagellin; fimbriae; rCTB; LPS; Ussing chamber; Galenisk farmaci; Pharmaceutics; Galenisk farmaci; galenisk farmaci; Pharmaceutics;

    Sammanfattning : Polyacryl starch microparticles have been developed as a new mucosal vaccine adjuvant intended for use in oral vaccination. The main objectives of this thesis were to evaluate the efficacy of these polyacryl starch microparticles and to study their uptake through mucosal tissues. LÄS MER

  7. 5. Infection biology of the plant pathogenic fungus Bipolaris sorokiniana

    Författare :Dace Apoga; Biologiska institutionen; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; microscopy; Hordeum vulgare; barley; virulence; prehelminthosporol; phytotoxins; proteins; adhesion; fimbriae; extracellular matrix; Helminthosporium sativum; Cochliobolus sativus; Plant pathogenic fungi; Bipolaris sorokiniana; two-dimensional gel electrophoresis; mass spectrometry; gas chromatography; Ecology; Ekologi;

    Sammanfattning : Bipolaris sorokiniana is a fungal pathogen causing severe disease mainly in wheat and barley worldwide. In this thesis two aspects of the infection process were investigated: the adhesion mechanism of the fungus and the role of the non-host specific phytotoxin prehelminthosporol (PHL) in the disease. Adhesion of B. LÄS MER