Sökning: "Gunnar Westin"

Visar resultat 11 - 15 av 24 avhandlingar innehållade orden Gunnar Westin.

1. 11. Small Intestinal Neuroendocrine Tumours : Genetic and Epigenetic Studies and Novel Serum Biomarkers

   Författare :Katarina Edfeldt; Peter Stålberg; Per Hellman; Gunnar Westin; Malin Sund; Endokrinkirurgi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; SI-NET; microarray; tumour suppressor gene; epigenetic; serum biomarkers; Kirurgi; Surgery;

   Sammanfattning : Small intestinal neuroendocrine tumours (SI-NETs) are rare, hormone producing and proliferate slowly. Patients usually display metastases at time of diagnosis, the tumours are difficult to cure, and the disease course is unpredictable. LÄS MER

3. 12. Pancreatic Endocrine Tumourigenesis : Genes of potential importance

   Författare :Térèse A. Johansson; Barbro Eriksson; Britt Skogseid; Gunnar Westin; Martin Bäckdahl; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pancreatic endocrine tumour; Multiple endocrine neoplasia type 1; Tumourigenesis; Notch signalling; Notch1; Hes1; Neurog3; Neurod1; Men1; Ascl1; Pou3f4; Pdx1; Rpl10; Dlk1; Dkk1; Tph1; menin; Tumour biology; Tumörbiologi;

   Sammanfattning : Understanding signalling pathways that control pancreatic endocrine tumour (PET) development and proliferation may reveal novel targets for therapeutic intervention. The pathogenesis for sporadic and hereditary PETs, apart from mutations of the MEN1 and VHL tumour suppressor genes, is still elusive. LÄS MER

4. 13. Carbothermal synthesis of nano-structured metal, carbides and nitrides, using solution processed precursors; from precursor to product

   Författare :Sarmad Naim Katea; Gunnar Westin; Hilmar Vidarsson; Sanjay Mathur; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Solution-based chemical processing; sol-gel; ceramic powders; transition metal carbides and nitrides; sintering; nickel binder; mechanical properties; Chemistry with specialization in Inorganic Chemistry; Kemi med inriktning mot oorganisk kemi;

   Sammanfattning : This thesis describes how solution chemical based carbothermal syntheses can be used for the synthesis of nanostructured zirconium carbide and nitride nanophase powders as well as a nickel-metal coating on NbC for use as a sintering agent. The focus is on the development of novel synthesis routes using atomic or small nanoscale level mixing of the metal oxide and carbon source in the starting precursors, enabling the use of lower synthesis temperatures and non-agglomerated nanosized powders. LÄS MER

5. 14. First-principle data-driven models for assessment of motor disorders in Parkinson’s disease

   Författare :Taha Khan; Peter Funk; Mark Dougherty; Jerker Westin; Shahina Begum; Gunnar Klein; Mälardalens högskola; []
   Nyckelord :Computer Science; datavetenskap; Complex Systems – Microdata Analysis;

   Sammanfattning : Parkinson’s disease (PD) is an increasing neurological disorder in an aging society. The motor and non-motor symptoms of PD advance with the disease progression and occur in varying frequency and duration. In order to affirm the full extent of a patient’s condition, repeated assessments are necessary to adjust medical prescription. LÄS MER

7. 15. Molecular Genetic Studies of Sporadic and MEN1-Associated Endocrine Pancreatic Tumors

   Författare :Daniel Lindberg; Gunnar Westin; Göran Åkerström; Bo Wängberg; Uppsala universitet; []
   Nyckelord :Surgery; pancreatic endocrine tumor; MEN1; LOH; WNT7A; HDAC11; CDK4; CDKN2B p15; CDKN1B p27; CDKN2C p18; c-Myc; Smad4; pyrosequencing; epigenetic; methylation; tumor suppressor; Kirurgi;

   Sammanfattning : Pancreatic endocrine tumors (PETs) may cause typical syndromes of hormone excess, or appear clinically non-functioning without hormonal symptoms. PETs occur sporadically, in association with the multiple endocrine neoplasia type 1 (MEN1) syndrome, or rarely the von Hippel-Lindau syndrome. LÄS MER