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Visar resultat 21 - 25 av 61 avhandlingar som matchar ovanstående sökkriterier.
21. PNA and affinity protein tools for selective tumor targeting of radiopharmaceuticals
Sammanfattning : Targeted radiotherapy of cancer intends to selectively deliver cytotoxic radionuclides to tumor cells. Affinity proteins of various kinds are explored for this task, and depending on the affinity protein used, different challenges arise. LÄS MER
22. Targeting HER2-expressing tumors with potent drug conjugates and fusion toxins based on scaffold proteins
Sammanfattning : Targeted therapy is an emerging treatment for a variety of cancers. Small- sized scaffold proteins are an alternative to conventional antibody-based targeting molecules. LÄS MER
23. Platforms and strategies harnessing signaling pathways of multifactorial diseases by multispecific antibodies
Sammanfattning : Abstract [ENG]Proteins govern a multitude of biological functions vital to sustain life. The ability to withstand diseases development and harboring a defense against foreign pathogens is attributed to the wonders of the immune system and the proteins and cells its comprised of. LÄS MER
24. Fluorescence-based ligand assays for protein detection using affibody affinity proteins
Sammanfattning : The detection and quantification of biomolecules, and proteins in particular, are of great interest since these molecules are of fundamental importance to our well-being. Body fluids, as for instance human blood, are well suited for sampling of protein levels. LÄS MER
25. Affibody-Based Molecular Imaging and Targeted Therapy of HER3-Expressing Cancer
Sammanfattning : The human epidermal growth factor receptor type 3 (HER3) is overexpressed in different types of cancer and is a known contributor to disease progression and resistance to cancer therapy. This thesis is based on five original articles, which aimed to improve the diagnostic and therapeutic potential of affibody-based agents for management of HER3-expressing cancers. LÄS MER