Sökning: "Immunotherapy"

Visar resultat 1 - 5 av 249 avhandlingar innehållade ordet Immunotherapy.

  1. 1. Cancer Immunotherapy : A Preclinical Study of Urinary Bladder Cancer

    Författare :Christina Ninalga; Thomas Tötterman; Magnus Essand; Timothy Ratliff; Uppsala universitet; []
    Nyckelord :Medicine; immunotherapy; bladder carcinoma; cancer; CpG ODNs; Adenoviral vector; CD40L; TRANCE; Lymphotactin; IL2; IL15; Medicin;

    Sammanfattning : Bacillus Calmette Guérin (BCG), or attenuated Mycobacterium bovis, is the gold standard of immunotherapy in the clinic to treat superficial bladder cancer. However, setbacks remain due to a high recurrence rate, side effects, and BCG-refractory disease. LÄS MER

  2. 2. Cancer Immunotherapy : Oncolytic viruses and CAR-T cells

    Författare :Jing Ma; Di Yu; Magnus Essand; Mia Phillipson; Mohanraj Ramachandran; Karl-Johan Malmberg; Uppsala universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cancer immunotherapy; Oncolytic viruses; chimeric antigen receptor CAR -T cells; Helicobacter pylori Neutrophil Activating Protein;

    Sammanfattning : Various forms of cancer immunotherapy have developed rapidly with improved survival and quality of life for cancer patients. Cancer immunotherapy aims to educate the patient’s immune system to eliminate cancer cells, including immune checkpoint inhibitors (ICIs), adoptive cell transfer (mostly T cells), oncolytic viruses (OVs) and cancer vaccines. LÄS MER

  3. 3. Cancer Immunotherapy : Evolving Oncolytic viruses and CAR T-cells

    Författare :Mohanraj Ramachandran; Magnus Essand; Di Yu; Justyna Leja-Jarblad; Richard Vile; Uppsala universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oncolytic virus; Adenovirus; Semliki Forest virus; Cancer immunology; Chimeric antigen receptor T-cells; Immunologi; Immunology; Oncology; Onkologi; Biology with specialization in Molecular Biotechnology; Biologi med inriktning mot molekylär bioteknik;

    Sammanfattning : In the last decade cancer immunotherapy has taken huge strides forward from bench to bedside and being approved as drugs. Cancer immunotherapy harnesses the power of patient’s own immune system to fight cancer. LÄS MER

  4. 4. Immunotherapy of children with rhinoconjunctivitis due to birch pollinosis

    Författare :Christian Möller; Umeå universitet; []
    Nyckelord :Birch pollinosis; Conjunctival provocation test; Crossed radioimmunoelectrophoresis; Crossreactivity tree pollens; Immunotherapy; Oral immunotherapy; Polyethyleneglycol absorption; Pollen counts; Rhinoconjunctivitis; Symptom score;

    Sammanfattning : In this investigation of immunotherapy (IT) children 6-16 years old with rhinoconjunctivitis due to birch polli­nosis were included.I. Methodological studies. To monitor IT a reliable provocation test is desirable. LÄS MER

  5. 5. Immunological mechanisms involved in seasonal pollen allergy and allergen-specific immunotherapy

    Författare :Robert Movérare; Uppsala universitet; []
    Nyckelord :Medical sciences; Allergy; birch pollen; IFN-g; IgE; IgG; IgG4; IL-4; IL-5; IL-10; IL-13; immunotherapy; PBMC; rush immunotherapy; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; lungmedicin; Lung Medicine;

    Sammanfattning : Th1/Th2-like T-cell responses were studied by stimulating peripheral blood mononuclear cells (PBMCs) with allergens or antigens followed by restimulation with mitogens to induce high cytokine synthesis. Allergen-stimulation in vitro induced Th2-skewed cytokine synthesis by PBMCs from birch-pollen-allergic patients. LÄS MER