Sökning: "virus assembly"

Visar resultat 6 - 10 av 64 avhandlingar innehållade orden virus assembly.

  1. 6. The role of the capsid protein in Semliki Forest virus assembly

    Författare :Kerstin Forsell; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Semliki Forest virus; RNA encapsidation; NC assembly; virus budding; RNA uncoating;

    Sammanfattning : Enveloped viruses, like the Alphaviruses, encapsidate their genomes into a nucleocapsid (NC) or core structure which is surrounded by a lipid bilayer (envelope) with spike proteins. The alphavirus Semliki Forest virus (SFV), is an RNA virus with a genomic 42 S RNA of positive polarity. LÄS MER

  3. 7. Viperin vs. tick-borne encephalitis virus : mechanism of a potent antiviral protein

    Författare :Kirstin Vonderstein; Anna Överby Wernstedt; Magnus Evander; Sonja Best; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Tick-borne encephalitis virus; TBEV; type-I interferon; IFN; Interferon-stimulated gene; ISG; viperin; GBF1; CIAO1; antiviral protein; genome replication; particle release; capsid;

    Sammanfattning : Tick-borne encephalitis virus (TBEV) is a very important virus medically, causing mild or severe encephalitis often with long-lasting sequelae. Treatment of tick-borne encephalitis is limited to supportive care, and antiviral drugs are much needed.The type-I interferon (IFN) system is the first line of host defense against many viruses. LÄS MER

  4. 8. Protein interactions involved in alphavirus assembly

    Författare :Ulrica Skoging Nyberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Alphavirus; Semliki Forest Virus; Virus assembly; Capsid Protein; Nucleocapsid; Viral Envelope Proteins;

    Sammanfattning : Viruses have to protect their genomes during transport from the infected to an uninfected host cell. This is achieved by forming a protein shell around the nucleic acid. Virus assembly is a complex process that involves interactions with the viral genome, the viral structural proteins and for enveloped viruses a lipid membrane. LÄS MER

  5. 9. Assembly of semliki forest and influenza A viruses

    Författare :Hongxing Zhao; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Semliki forest virus; influenza virus; virus budding.;

    Sammanfattning : Enveloped viruses contain an external lipid membrane with spikes surrounding their nucleocapsid (NC). The envelope is acquired at a late stage of virus assembly by budding of the NC through a virus-modified host membrane. LÄS MER

  7. 10. Structure of small RNA phages

    Författare :Kaspars Tars; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Developmental biology; bacteriophage; MS2; virus assembly; structural evolution; Utvecklingsbiologi; Developmental biology; Utvecklingsbiologi; molekylärbiologi; Molecular Biology;

    Sammanfattning : Small RNA phages belonging to the family Leviviridae are among the simplest known viruses. They have been used extensively as models for studies of various problems in molecular biology, including protein-RNA interactions, repression of translation, virus assembly and virus evolution. LÄS MER