Sökning: "Semliki forest virus"
Visar resultat 1 - 5 av 29 avhandlingar innehållade orden Semliki forest virus.
1. Assembly and entry mechanisms of Semliki Forest virus
Sammanfattning : The genomes of enveloped viruses are packaged into a core or nucleocapsid (NC) which is surrounded by a lipid membrane with spike proteins. These viruses mature by budding at a membrane of the host cell, usually the plasma membrane (PM), and penetrate into new ones by a virus-host membrane fusion event. LÄS MER
2. Tumor gene therapy using Semliki forest virus replicons
Sammanfattning : A major challenge in cancer research is to design effective vaccines that can break immunological tolerance to tumor antigens. Over the past ten years several immunotherapeutic strategies aimed at modulating the patient's immune response to fight cancer have been tested in clinical trials. LÄS MER
3. Assembly of semliki forest and influenza A viruses
Sammanfattning : Enveloped viruses contain an external lipid membrane with spikes surrounding their nucleocapsid (NC). The envelope is acquired at a late stage of virus assembly by budding of the NC through a virus-modified host membrane. LÄS MER
4. The role of the capsid protein in Semliki Forest virus assembly
Sammanfattning : Enveloped viruses, like the Alphaviruses, encapsidate their genomes into a nucleocapsid (NC) or core structure which is surrounded by a lipid bilayer (envelope) with spike proteins. The alphavirus Semliki Forest virus (SFV), is an RNA virus with a genomic 42 S RNA of positive polarity. LÄS MER
5. Semliki forest virus-derived packaging system for production of retroviral vectors
Sammanfattning : Gene therapy is a treatment of disease by transfer of genetic material into somatic cells of an individual. Successful gene therapy depends on a delivery system which can efficiently transfer the gene into target cells and lead to high level expression of the gene. LÄS MER