Sökning: "bacteriophage"

Visar resultat 1 - 5 av 65 avhandlingar innehållade ordet bacteriophage.

  1. 1. Structural Studies of Bacteriophage PRR1 and HIV-1 protease

    Detta är en avhandling från Uppsala : Uppsala Universitatis Upsaliensis

    Författare :Magnus Persson; Uppsala universitet.; [2010]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; PRR1; HIV; Structural Biology; X-ray crystallography; PRR1; HIV-1 protease; NCS; crystallography; inhibitor; virus; bacteriophage; X-ray crystallography; MEDICINE Microbiology; immunology; infectious diseases Microbiology Virology; MEDICIN Mikrobiologi; immunologi; infektionssjukdomar Mikrobiologi Virologi; MEDICINE Dermatology and venerology; clinical genetics; internal medicine Clinical genetics Molecular biology; MEDICIN Dermatologi och venerologi; klinisk genetik; invärtesmedicin Klinisk genetik Molekylärbiologi;

    Sammanfattning : Viruses are a diverse genera of organisms adapted to thrive in many different hosts from prokaryotic to eukaryotic.We present here the structure of bacteriophage PRR1 virus-like particle (VLP), belonging to Leviviridae family. Our structure reveals calcium ions in the VLP. LÄS MER

  2. 2. Control of Quasi-Equivalence in Virus Capsids

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Charlotte Helgstrand; Uppsala universitet.; [2002]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Cell and molecular biology; crystallography; bacteriophage; virus; RNA; capsid; quasi-equivalence; assembly; Cell- och molekylärbiologi; NATURAL SCIENCES Biology Cell and molecular biology; NATURVETENSKAP Biologi Cell- och molekylärbiologi; Molecular Biotechnology; Molekylär bioteknik;

    Sammanfattning : Many T=3 plant and insect viruses use a molecular switch in form of order/disorder of a segment of the polypeptide chain to regulate the quasi-equivalent contacts. The structure of a mutant of the T=3 capsid of bacteriophage fr confirms that this virus and other members of the Leviviridae family lack a switch mechanism. LÄS MER

  3. 3. Structure-Function Studies of Bacteriophage P2 Integrase and Cox protein

    Detta är en avhandling från Stockholm : Institutionen för genetik, mikrobiologi och toxikologi

    Författare :Jesper Eriksson; Stockholms universitet.; [2005]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Bacteriophage P2; site-specific recombination; integrase; transcriptional switch; NATURAL SCIENCES Biology Cell and molecular biology Genetics; NATURVETENSKAP Biologi Cell- och molekylärbiologi Genetik;

    Sammanfattning : Probably no group of organisms has been as important as bacteriophages when it comes to the understanding of fundamental biological processes like transcriptional control, DNA replication, site-specific recombination, e.t.c.The work presented in this thesis is a contribution towards the complete understanding of these organisms. LÄS MER

  4. 4. Group I Introns and Homing Endonucleases in T-even-like Bacteriophages

    Detta är en avhandling från Stockholm : Institutionen för molekylärbiologi och funktionsgenomik

    Författare :Linus Sandegren; Stockholms universitet.; [2004]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Bacteriophage; Self-splicing introns; Homing endonucleases; NATURAL SCIENCES Biology Cell and molecular biology Molecular biology; NATURVETENSKAP Biologi Cell- och molekylärbiologi Molekylärbiologi;

    Sammanfattning : Homing endonucleases are rare-cutting enzymes that cleave DNA at a site near their own location, preferentially in alleles lacking the homing endonuclease gene (HEG). By cleaving HEG-less alleles the homing endonuclease can mediate the transfer of its own gene to the cleaved site via a process called homing, involving double strand break repair. LÄS MER

  5. 5. The type I-E CRISPR-Cas system Biology and applications of an adaptive immune system in bacteria

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Lina Amlinger; Uppsala universitet.; [2017]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; CRISPR; CRISPR-Cas; virus defense; bacteria; bacteriophage; adaptation; spacer integration; interference; gene silencing; fluorescent reporter; Escherichia coli; Mikrobiologi; Microbiology;

    Sammanfattning : CRISPR-Cas systems are adaptive immune systems in bacteria and archaea, consisting of a clustered regularly interspaced short palindromic repeats (CRISPR) array and CRISPR associated (Cas) proteins. In this work, the type I-E CRISPR-Cas system of Escherichia coli was studied.CRISPR-Cas immunity is divided into three stages. LÄS MER