Sökning: "TBEV"
Visar resultat 1 - 5 av 26 avhandlingar innehållade ordet TBEV.
1. Viperin vs. tick-borne encephalitis virus : mechanism of a potent antiviral protein
Sammanfattning : Tick-borne encephalitis virus (TBEV) is a very important virus medically, causing mild or severe encephalitis often with long-lasting sequelae. Treatment of tick-borne encephalitis is limited to supportive care, and antiviral drugs are much needed.The type-I interferon (IFN) system is the first line of host defense against many viruses. LÄS MER
2. The role of the type I interferons and viperin during neurotropic flavivirus infection
Sammanfattning : Flaviviruses are globally distributed pathogens that cause millions of human infections annually. One of the most detrimental outcomes of flavivirus infection is encephalitis, which is caused by neurotropic flaviviruses such as West Nile virus (WNV), Japanese encephalitis virus (JEV), and Tick-borne encephalitis virus (TBEV). LÄS MER
3. Roles of mammalian Scribble in polarity signaling, virus offense and cell-fate determination
Sammanfattning : Mammalian Scribble is a target for proteins encoded by human papilloma virus, retro- and flaviviruses. Tick-borne encephalitis virus (TBEV) is a flavivirus that have evolved distinct strategies to escape antiviral responses. LÄS MER
4. Identification of protease inhibitors against Flaviviruses and Coronaviruses
Sammanfattning : Vector-borne flaviviruses and coronaviruses of zoonotic origins are important human pathogens and represent a serious threat to public health worldwide. Flaviviruses can be found on all continents, apart from Antarctica, where they are transmitted by arthropod vectors causing millions of infections every year. LÄS MER
5. Exploration of analytical methods to study motif-mediated host-virus protein-protein interactions
Sammanfattning : Proteins are responsible for countless processes in living creatures, but most often they do not perform these tasks alone. Rather, they engage in interactions with other proteins, creating whole protein-protein interaction (PPI) networks. LÄS MER