Sökning: "TBEV"

Visar resultat 1 - 5 av 20 avhandlingar innehållade ordet TBEV.

  1. 1. Viperin vs. tick-borne encephalitis virus : mechanism of a potent antiviral protein

    Författare :Kirstin Vonderstein; Anna Överby Wernstedt; Magnus Evander; Sonja Best; Umeå universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Tick-borne encephalitis virus; TBEV; type-I interferon; IFN; Interferon-stimulated gene; ISG; viperin; GBF1; CIAO1; antiviral protein; genome replication; particle release; capsid;

    Sammanfattning : Tick-borne encephalitis virus (TBEV) is a very important virus medically, causing mild or severe encephalitis often with long-lasting sequelae. Treatment of tick-borne encephalitis is limited to supportive care, and antiviral drugs are much needed.The type-I interferon (IFN) system is the first line of host defense against many viruses. LÄS MER

  2. 2. The role of the type I interferons and viperin during neurotropic flavivirus infection

    Författare :Richard Lindqvist; Anna Överby Wernstedt; Daniel Ruzek; Umeå universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TBEV; Flavivirus; Interferon; Neurotropic; Viperin;

    Sammanfattning : Flaviviruses are globally distributed pathogens that cause millions of human infections annually. One of the most detrimental outcomes of flavivirus infection is encephalitis, which is caused by neurotropic flaviviruses such as West Nile virus (WNV), Japanese encephalitis virus (JEV), and Tick-borne encephalitis virus (TBEV). LÄS MER

  3. 3. Roles of mammalian Scribble in polarity signaling, virus offense and cell-fate determination

    Författare :Michael Wigerius; Magnus Johansson; Lawrence Banks; Stockholms universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; cell polarity; scribble; tbev; RhoGTPase; jak-stat; mapk; neurite outgrowth; influenza a virus; Biochemistry; Biokemi; biokemi; Biochemistry;

    Sammanfattning : Mammalian Scribble is a target for proteins encoded by human papilloma virus, retro- and flaviviruses. Tick-borne encephalitis virus (TBEV) is a flavivirus that have evolved distinct strategies to escape antiviral responses. LÄS MER

  4. 4. Functional characterization of interactions between the flavivirus NS5 protein and PDZ proteins of the mammalian host

    Författare :Karin Ellencrona; Magnus Johansson; Andrew Davidson; Stockholms universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Tick-borne encephalitis virus TBEV ; West-Nile virus WNV ; Dengue virus DENV ; flavivirus; PDZ domains; ZO-2; ZO-1; RIMS2; Scribble; Interferon; JAK-STAT signaling; PDZ array; virus-host protein interaction; Genetics; Genetik; molekylärgenetik; Molecular Genetics;

    Sammanfattning : Flaviviruses are found all over the world and affect and infect millions of people every year. Flavivirus infection can lead to severe clinical outcomes resulting in neuronal damages e.g. Tick-borne encephalitis virus (TBEV), or severe hemorrhagic fevers e. LÄS MER

  5. 5. Ticks and Tick-borne Encephalitis Virus : From Nature to Infection

    Författare :Naveed Asghar; Magnus Johansson; Patrik Dinnétz; Travis Taylor; Södertörns högskola; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Co-occurrence; Environmental factors; Flavivirus; Ixodes ricinus; Natural foci; Non-coding region; Poly A tract; Quasispecies; Questing ticks; Scandinavia; Tick-borne encephalitis virus; Vegetation.; Environmental Studies; Miljövetenskapliga studier;

    Sammanfattning : Vector-borne diseases are an increasing global threat to humans due to climate changes, elevating the risk of infections transmitted by mosquitos, ticks, and other arthropod vectors. Ixodes ricinus, a common tick in Europe, transmits dangerous tick-borne pathogens to humans. LÄS MER