Sökning: "peripheral nerve injury"
Visar resultat 1 - 5 av 97 avhandlingar innehållade orden peripheral nerve injury.
1. Cell activation and nerve regeneration following peripheral nerve injury
Sammanfattning : The effect of short time vibration exposure and tourniquet compression on nerve regeneration in rats was studied with special reference to cell activation. One of the hindlimbs was conditioned by either vibration exposure (5 hours / day - 5 consecutive days) or compression (150-300 mmHg for 30-120 minutes), which was followed by a recovery period of 0-7 days. LÄS MER
2. Peripheral nerve reconstruction. Studies on cellular and acellular iso-, allo- and xenografts
Sammanfattning : The best results after a nerve injury with a defect are achieved by a nerve reconstruction procedure using autologous nerve grafts. However, limitations include insufficient amount of suitable donor material and donor site morbidity. The aim of the present thesis was to study alternative nerve grafts, i.e. LÄS MER
3. Phospholipase A2 in nerve injury and axonal outgrowth
Sammanfattning : This thesis deals with processes coupled to injury in the peripheral nervous system (PNS), with a general aim to investigate the role of phospholipase A2 (PLA2) enzymes in axonal outgrowth. The axonal outgrowth of dorsal root ganglia (DRG) neurons in vitro was reduced by several different inhibitors of PLA2 activity and enhanced by an activator of this enzyme. LÄS MER
4. Sensory neuronal protection & improving regeneration after peripheral nerve injury
Sammanfattning : Peripheral nerve trauma is a common cause of considerable functional morbidity, and healthcare expenditure. Particularly in the ~15% of injuries unsuitable for primary repair, standard clinical management results in inadequate sensory restitution in the majority of cases, despite the rigorous application of complex microsurgical techniques. LÄS MER
5. Development of biosynthetic conduits for peripheral nerve repair
Sammanfattning : Peripheral nerve injuries are often associated with significant loss of nervous tissue leading to poor restoration of function following repair of injured nerves. Although the injury gap could be bridged by autologous nerve graft, the limited access to donor material and additional morbidity such as loss of sensation and scarring have prompted a search for biosynthetic nerve transplants. LÄS MER