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Visar resultat 11 - 15 av 184 avhandlingar som matchar ovanstående sökkriterier.

  1. 11. Covariate Model Building in Nonlinear Mixed Effects Models

    Författare :Jakob Ribbing; E. Niclas Johnsson; Mats O. Karlsson; Janet Wade; Uppsala universitet; []
    Nyckelord :Pharmacokinetics Pharmacotherapy; Pharmacokinetics; Pharmacodynamics; Modeling; Covariate selection; Stepwise selection; Covariate analysis; Methodology; Model validation; Model evaluation; Type-2 diabetes; Beta-cell function; Meta analysis; Cross-validation; Least absolute shrinkage and selection operator; Pharmacometrics; ED optimization; Farmakokinetik Farmakoterapi;

    Sammanfattning : Population pharmacokinetic-pharmacodynamic (PK-PD) models can be fitted using nonlinear mixed effects modelling (NONMEM). This is an efficient way of learning about drugs and diseases from data collected in clinical trials. LÄS MER

  2. 12. Sex, Sperm and Speciation : On sexual selection and fertility in hybridizing flycatchers

    Författare :Murielle Ålund née Podevin; Anna Qvarnström; Simone Immler; Leonie Moyle; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; sperm biology; sexual selection; speciation; hybridization; cryptic female choice; fertility; Ficedula flycatchers; Biologi med inriktning mot zooekologi; Biology with specialization in Animal Ecology;

    Sammanfattning : Sexual reproduction entails complex co-evolution between the sexes, necessary for successful fertilization, ensuring individual and population-level fitness. Interfertility is the main criterion for species definition and understanding speciation requires detailed studies of reproductive barriers. LÄS MER

  3. 13. Fishing for Females : Sensory Exploitation in the Swordtail Characin

    Författare :Mirjam Amcoff; Niclas Kolm; Michael Ryan; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Sexual selection; Mate choice; Courtship; Sensory bias; Plasticity; Corynopoma riisei; Mulitiple signalling; Biologi med inriktning mot zooekologi; Biology with specialization in Animal Ecology;

    Sammanfattning : Mate choice plays an important role in sexual selection and speciation. The evolution of mate choice is intriguing in cases where choosy individuals gain little except for genetic material from the mate and where the trait used as a criterion for the choice is costly to its bearer. LÄS MER

  4. 14. Att skapa ett kulturarv

    Författare :Vivian Smits; Cornelius Holtorf; Ola W. Jensen; Linnéuniversitetet; []
    Nyckelord :HUMANIORA; HUMANITIES; cultural heritage; contract archaeology; museum collection; material culture; selection; cultural heritage paradox; kulturarv; uppdragsarkeologi; samling; källmaterial; gallring; urval; kulturarvsparadox; Archaeology; Arkeologi;

    Sammanfattning : Det övergripande målet för detta arbete ligger i att utveckla samarbetet mellan aktörerna i det uppdragsarkeologiska verksamhetsfältet, i syfte att optimera urvalet och användningen av de ting som genereras och blir till ett kulturarv. Tyngdpunkten i licentiatuppsatsen ligger på de processer och strukturer som ligger till grund för formering av samlingarna och genom vilka det arkeologiska källmaterialet får en ny identitet som musealt kulturarv. LÄS MER

  5. 15. The Onset of Ethnic War as a Bargaining Process : Testing a Signaling Model

    Författare :Magnus Öberg; Han Dorussen; Uppsala universitet; []
    Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Peace and conflict research; ethnic conflict; civil war; escalation; bargaining; game theory; signaling; selection bias; Freds- och konfliktforskning; Peace and conflict research; Freds- och konfliktforskning; Peace and Conflict Research; Freds- och konfliktforskning;

    Sammanfattning : Most theories of ethnic conflict explain ethnic war by reference to the factors that motivate and enable ethnic groups to rebel. To rebel is to rise up against or challenge government authority; but for war to be the outcome of a challenge the government must attempt to forcefully reassert its authority. LÄS MER